Cardiovascular Risk in Diabetes Mellitus: Complication of the Disease or of Antihyperglycemic Medications.
Cardiovascular Risk in Diabetes Mellitus: Complication of the Disease or of Antihyperglycemic Medications.
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DOI：
10.1002/cpt.143
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发表时间：
2015-08
影响因子：
6.7
通讯作者：
McGuire DK
中科院分区：
文献类型：
--
作者：
Alvarez CA;Lingvay I;Vuylsteke V;Koffarnus RL;McGuire DK
心血管疾病是糖尿病（DM）患者的主要并发症和主要死亡原因。抗高血糖治疗对心血管疾病风险的疗效仍不确定。心血管危险因素受到抗高血糖药物的影响，心血管疾病的许多中间标志物也是如此。在这里，我们总结了评估抗高血糖药物的心血管作用的危险因素，疾病的中间标志物和临床结果的证据。
Cardiovascular disease is the principal complication and the leading cause of death for patients with diabetes (DM). The efficacy of anti-hyperglycemic treatments on cardiovascular disease risk remains uncertain. Cardiovascular risk factors are affected by anti-hyperglycemic medications, as are many intermediate markers of cardiovascular disease. Here we summarize the evidence assessing the cardiovascular effects of anti-hyperglycemic medications with regards to risk factors, intermediate markers of disease, and clinical outcomes.