Effects of ISI and stimulus probability on event-related go/nogo potentials after somatosensory stimulation
Effects of ISI and stimulus probability on event-related go/nogo potentials after somatosensory stimulation
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DOI：
10.1007/s00221-004-2195-4
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发表时间：
2005-04-01
影响因子：
2
通讯作者：
Kakigi, R
中科院分区：
文献类型：
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作者：
Nakata, H;Inui, K;Kakigi, R
采用体感go/nogo任务研究了事件相关电位（ERPs）中潜伏期负电位的特点。实验1操纵刺激间隔（ISI），实验2操纵刺激概率，分析go刺激诱发的ERP与nogo刺激诱发的ERP相减后的差值波形。实验1中，负波潜伏期随ISI的增加而显著延长，而负波波幅无明显变化。反应时（RT）随ISI的增加而延长。在实验2中，操纵的刺激概率产生了增加的峰值振幅与nogo刺激的概率降低，但不影响潜伏期。RT随着Nogo刺激计划的可能性上升而上升。由于操纵的ISI和刺激概率引起不同的大脑活动，我们假设，操纵的ISI引起延迟的刺激评价过程，包括反应抑制，刺激概率显着影响反应抑制过程的强度。
The present study investigated the characteristics of the middle-latency negative potential of event-related potentials (ERPs) using somatosensory go/nogo tasks. We manipulated interstimulus interval (ISI) in Experiment 1 and stimulus probability in Experiment 2 and analyzed the subtracted difference waveform resulting from subtraction of the ERP evoked by the go stimulation from that evoked by the nogo stimulation. In Experiment 1, the peak latency of negativity became significantly longer as the ISI increased, but the peak amplitude was unchanged. The reaction time (RT) was longer with increasing ISI. In Experiment 2, manipulation of the stimulus probability yielded an increase in peak amplitude with decreasing probability of the nogo stimulus, but did not affect the latency. The RT increased as the probability of a nogo stimulus rose. Because manipulation of the ISI and stimulus probability elicited different brain activities, we hypothesized that manipulation of the ISI elicited a delay of the stimulus evaluation process including response inhibition, and that stimulus probability significantly affected the strength of the response inhibition process.