ROUTINE QUANTITATIVE-ANALYSIS OF BRAIN AND CEREBROSPINAL-FLUID SPACES WITH MR IMAGING
ROUTINE QUANTITATIVE-ANALYSIS OF BRAIN AND CEREBROSPINAL-FLUID SPACES WITH MR IMAGING
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DOI：
10.1002/jmri.1880020603
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发表时间：
1992-11-01
期刊：
影响因子：
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通讯作者：
JOLESZ, FA
中科院分区：
文献类型：
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作者：
KIKINIS, R;SHENTON, ME;JOLESZ, FA
一个计算机化的系统，用于处理自旋回波磁共振（MR）成像数据，估计全脑（灰色和白色物质）和脑脊液体积，并显示三维表面重建的指定组织类。通过评估MR体积数据的辐射变异性以及比较用于测量组织体积的自动和手动程序，对这些技术进行了评价。结果表明：（a）MR数据的均匀性和（B）自动化技术始终优于手动技术上级。然而，这两种技术都受到结构复杂性的影响，较简单的结构（如颅内腔）显示出较小的变异性和评分者之间分割结果的更好的空间相关性。此外，自动化技术完成了整个大脑在所需的时间的一小部分，以完成等效的分割手动。其他评价包括评价者间可靠性和包括纵向测量的评价，其中一名受试者连续成像24次，可靠性根据3名评价者在1年内收集的数据计算。结果表明，自动分割程序具有良好的可靠性。
A computerized system for processing spin-echo magnetic resonance (MR) imaging data was implemented to estimate whole brain (gray and white matter) and cerebrospinal fluid volumes and to display three-dimensional surface reconstructions of specified tissue classes. The techniques were evaluated by assessing the radiometric variability of MR volume data and by comparing automated and manual procedures for measuring tissue volumes. Results showed (a) the homogeneity of the MR data and (b) that automated techniques were consistently superior to manual techniques. Both techniques, however, were affected by the complexity of the structure, with simpler structures (eg, the intracranial cavity) showing less variability and better spatial correlation of segmentation results between raters. Moreover, the automated techniques were completed for whole brain in a fraction of the time required to complcte the equivalent segmentation manually. Additional evaluations included interrater reliability and an evaluation that included longitudinal measurement, in which one subject was imaged sequentially 24 times, with reliability computed from data collected by three raters over 1 year. Results showed good reliability for the automated segmentation procedures.