Increasing Public Awareness of Direct-to-Consumer Genetic Tests: Health Care Access, Internet Use, and Population Density Correlates
Increasing Public Awareness of Direct-to-Consumer Genetic Tests: Health Care Access, Internet Use, and Population Density Correlates
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DOI：
10.1155/2012/309109
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发表时间：
2012-01-01
影响因子：
1.8
通讯作者：
Moser, Richard P.
中科院分区：
文献类型：
--
作者：
Rutten, Lila J. Finney;Gollust, Sarah E.;Moser, Richard P.
围绕直接面向消费者（DTC）基因检测的价值和适当监管模式的不确定性强调了跟踪公众对这些服务的认识的重要性。我们分析了2008年（n = 7，674）和2011年（n = 3，959）健康信息全国趋势调查的全国代表性横断面数据，以评估美国DTC基因检测意识的人口水平变化，并探索社会人口统计学，医疗保健，互联网使用和人口密度相关性。总体而言，认识率从2008年的29%大幅提高到2011年的37%。从2008年到2011年，观察到的认识增加仍然显着（OR = 1.39），即使调整了社会人口变量，医疗保健，互联网使用和人口密度。与调查年份无关，50-64岁的人对DTC基因检测的知晓率显著较高（OR = 1.64），65-74（OR = 1.60）;大学毕业生（OR = 2.02）;有固定的卫生保健来源者（OR = 1.27）;既往诊断为癌症的人（OR = 1.24）;使用互联网的人（OR = 1.27）;以及居住在城市地区的人（OR = 1.25）。监测的认识，以及经验数据的使用和应对遗传风险的信息，可以告知公共卫生和政策的努力，以最大限度地提高利益和最大限度地减少DTC基因检测的风险。
Uncertainty around the value of and appropriate regulatory models for direct-to-consumer (DTC) genetic testing underscores the importance of tracking public awareness of these services. We analyzed nationally representative, cross-sectional data from the Health Information National Trends Survey in 2008 (n = 7, 674) and 2011 (n = 3, 959) to assess population-level changes in awareness of DTC genetic testing in the U.S. and to explore sociodemographic, health care, Internet use, and population density correlates. Overall, awareness increased significantly from 29% in 2008 to 37% in 2011. The observed increase in awareness from 2008 to 2011 remained significant (OR = 1.39) even when adjusted for sociodemographic variables, health care access, Internet use, and population density. Independent of survey year, the odds of awareness of DTC genetic tests were significantly higher for those aged 50-64 (OR = 1.64), and 65-74 (OR = 1.60); college graduates (OR = 2.02); those with a regular source of health care (OR = 1.27); those with a prior cancer diagnosis (OR = 1.24); those who use the Internet (OR = 1.27); and those living in urban areas (OR = 1.25). Surveillance of awareness-along with empirical data on use of and response to genetic risk information-can inform public health and policy efforts to maximize benefits and minimize risks of DTC genetic testing.