Addressing fear of cancer recurrence among women with cancer: a feasibility and preliminary outcome study
Addressing fear of cancer recurrence among women with cancer: a feasibility and preliminary outcome study
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DOI：
10.1007/s11764-014-0357-3
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发表时间：
2014-09-01
影响因子：
3.7
通讯作者：
Catton, Pamela
中科院分区：
文献类型：
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作者：
Lebel, Sophie;Maheu, Christine;Catton, Pamela
背景证据表明，对癌症复发的恐惧（FCR）是癌症幸存者中最常提到的未满足的需求之一，并与心理困扰、压力反应症状、生活质量下降以及医疗保健资源的使用增加有关。尽管存在这些因素，但很少有手动干预措施可以解决癌症幸存者的 FCR 问题。 目的 开发、手动化和试点测试旨在解决乳腺癌或卵巢癌女性 FCR 问题的 6 周认知存在 (CE) 团体干预措施的可行性和初步疗效。 方法 本研究是一项单组多中心研究，具有术前、术后和 3 个月的随访测量时机。结果 共有 56 名乳腺癌或卵巢癌幸存者参加了该研究； 44人完成CE组干预。干预后，女性的 FCR 主要研究结果指标和癌症特异性痛苦和不确定性的次要研究结果指标有所下降。他们还报告了生活质量和应对的二级研究结果指标的改善。观察到的变化的效应大小大部分处于中到大效应范围内；此外，几乎所有变化在 3 个月的随访中得以维持。结论 这种简短的干预似乎是可行的，并且在解决 FCR 和癌症特异性痛苦、不确定性、生活质量和应对等相关次要结局方面显示出有希望的结果；然而，应该使用随机对照研究设计进行进一步测试，以更明确地评估其功效。 对癌症幸存者的影响 FCR 是癌症幸存者几乎普遍担心的问题，如果不加以解决，随着时间的推移，FCR 往往会保持稳定。这项研究对所有癌症幸存者具有重要意义，因为它是第一个发表的干预措施，提供了其在减少对癌症复发的恐惧方面的功效的初步证据。
Background Evidence suggests that fear of cancer recurrence (FCR) is one of the most frequently cited unmet needs among cancer survivors and is associated with psychological distress, stress-response symptoms, and lower quality of life, as well as increased use of health care resources. Despite these factors, few manualized interventions exist to address FCR among cancer survivors.Purpose To develop, manualize, and pilot test the feasibility and preliminary efficacy of a 6-week cognitive-existential (CE) group intervention designed to address FCR in women with breast or ovarian cancer.Methods This study was a single-arm multi-site study with pre-, post-, and 3-month follow-up measurement occasions. Results A total of 56 breast or ovarian cancer survivors enrolled in the study; 44 completed the CE group intervention. Following the intervention, women experienced a reduction in the primary study outcome measure of FCR and secondary study outcome measures of cancer-specific distress and uncertainty. They also reported improvements in secondary study outcome measures of quality of life and coping. The effect sizes of the observed changes were for the most part in the medium to large effect range; furthermore, almost all changes were sustained at 3-month follow-up.Conclusion This brief intervention appears feasible and has shown promising results in addressing FCR and related secondary outcomes of cancer-specific distress, uncertainty, quality of life, and coping; however, it should be further tested using a randomized controlled study design to more definitively assess its efficacy.Implications for Cancer Survivors FCR is a near-universal worry for cancer survivors that, when left unaddressed, tends to remain stable over time. This study has important implications for all cancer survivors as it is the first published intervention that provides preliminary evidence of its efficacy in decreasing fear of cancer recurrence.