Joint space in radiologically normal knees.
Joint space in radiologically normal knees.
复制标题
放射学正常膝盖的关节间隙。
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
E. Huskisson
中科院分区：
文献类型：
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作者：
J. Dacre;D. L. Scott;J. A. P. DA SILVA;G. Welsh;E. Huskisson
关节间隙丢失是类风湿性关节炎和骨关节炎的特征。然而，如果不了解关节间隙大小的正常变异性，则无法对其进行充分评价。我们测量了关节间隙的大小，使用数字图像分析在人口的放射学正常的个人。研究了685名连续的因不明原因的膝关节疼痛或外伤，但没有关节炎的临床或放射学证据的患者的膝关节前后位片。结果表明，在放射学正常的人群中，男性的关节间隙比女性大，并且关节间隙大小随着年龄的增长而稳步下降。我们发现负重和非负重女性的关节间隙大小没有显著差异。疼痛患者和受伤后出现疼痛的患者也没有差异。在213例患者的亚组中，正常关节间隙大小与身高、体重或体重指数无关。我们认为，随着年龄的增长，患者失去关节间隙，并最终达到骨关节炎症状发生的“疼痛阈值”。这就解释了那些开始关节间隙较小的人，即妇女和老年人，关节症状的增加。
Joint space loss is a characteristic feature of rheumatoid arthritis and osteoarthritis. It cannot be fully evaluated, however, without knowledge of the normal variability of joint space size. We have measured joint space size using digital image analysis in a population of radiologically normal individuals. Anteroposterior films of the knee were studied from 685 consecutive patients attending Casualty with unexplained knee pain or following trauma, but with no clinical or radiological evidence of arthritis. Results show that in a radiologically normal population, men have larger joint spaces than women and there is a steady decline in joint space size with age. We found no significant difference in joint space size between weight bearing and non-weight bearing women. There was also no difference in patients presenting with pain and those presenting following an injury. Normal joint space size was not related to height, weight or body mass index in a subgroup of 213 patients. We suggest that patients lose joint space with increasing age and eventually reach a 'pain threshold' at which symptoms of osteoarthritis occur. This explains the increase in joint symptoms in those who begin with smaller joint spaces; that is in women and in the elderly.