Biodegradable fixation for craniomaxillofacial surgery: a 10-year experience involving 761 operations and 745 patients.
Biodegradable fixation for craniomaxillofacial surgery: a 10-year experience involving 761 operations and 745 patients.
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DOI：
10.1016/j.ijom.2010.11.024
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发表时间：
2011-03
影响因子：
2.4
通讯作者：
Phillips C
中科院分区：
文献类型：
--
作者：
Turvey TA;Proffit WP;Phillips C
本文报告了聚-L/DL-乳酸（PLLDL）接骨板和螺钉在颅颌面外科中的患者接受度、安全性和有效性。样本中包括745名患者，他们接受了761次单独的手术，包括1400多次外科手术（正颌手术（685），骨移植重建（37），创伤（191）和经颅手术（20））。成功率（无断裂或炎症需要额外的手术室治疗）为94%。由于断裂（14）或过度炎症（31）而发生失效。所有断裂均发生在下颌部位，大多数炎性衰竭发生在上颌骨或眼眶（29），只有2例发生在下颌骨。故障平均分布在两个主要供应商之间。PLLDL 70/30接骨板和螺钉可成功用于各种颅颌面外科应用。优点包括生理力逐渐转移到愈合的骨骼，减少了对第二次手术去除材料的需要，以及其作为将骨愈合蛋白递送到骨折/截骨部位的载体的潜力。在所有部位均观察到骨愈合，即使是在需要第二次手术干预的旺盛炎症部位。
Patient acceptance, safety, and efficacy of poly-L/DL-lactic acid (PLLDL) bone plates and screws in craniomaxillofacial surgery are reported in this article. Included in the sample are 745 patients who underwent 761 separate operations, including more than 1400 surgical procedures (orthognathic surgery (685), bone graft reconstruction (37), trauma (191) and transcranial surgery (20)). The success (no breakage or inflammation requiring additional operating room treatment) was 94%. Failure occurred because of breakage (14) or exuberant inflammation (31). All breakage occurred at mandibular sites and the majority of inflammatory failure occurred in the maxilla or orbit (29), with only two in the mandible. Failures were evenly distributed between the two major vendors. PLLDL 70/30 bone plates and screws may be used successfully in a variety of craniomaxillofacial surgical applications. The advantages include the gradual transference of physiological forces to the healing bone, the reduced need for a second operation to remove the material and its potential to serve as a vehicle to deliver bone-healing proteins to fracture/osteotomy sites. Bone healing was noted at all sites, even where exuberant inflammation required a second surgical intervention.
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