Daytime-to-Nighttime Sleep Ratios and Cognitive Impairment in Older Intensive Care Unit Survivors.
Daytime-to-Nighttime Sleep Ratios and Cognitive Impairment in Older Intensive Care Unit Survivors.
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DOI：
10.4037/ajcc2021221
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发表时间：
2021-03-01
期刊：
影响因子：
--
通讯作者：
Liang Z
中科院分区：
文献类型：
--
作者：
Elías MN;Munro CL;Liang Z
睡眠持续时间和白天与夜间睡眠的比例可能会影响老年患者从重症监护室过渡的认知功能。探讨老年重症监护病房幸存者日间夜间睡眠比例与认知功能障碍的关系。该研究在重症监护室出院后24至48小时内招募了30名老年人。所有参与者在入院前功能独立，并在重症监护室接受机械通气。活动计用于估计白天（上午6点到晚上9点59分）和夜间（晚上10点到上午5点59分）的总睡眠时间。白天与夜间的睡眠比率是通过白天睡眠的比例除以夜间睡眠的比例来计算的。采用美国国立卫生研究院认知成套测验维度变化卡片分类测验（DCCST）评估认知。调整协变量后，使用多变量回归探讨睡眠和认知之间的关联。平均（SD）日间睡眠时间为7.55（4.30）小时（范围：0.16-14.21小时），平均（SD）夜间睡眠时间为4.99（1.95）小时（范围：0.36-7.21小时）。平均（SD）日间与夜间睡眠比率为0.71（0.30）（范围：0.03-1.10）。更长的白天睡眠时间（β =-0.351，P = 0.008）和更高的白天与夜间睡眠比率（β =-0.373，P = 0.008）与DCCST评分呈负相关。在研究人群中，白天与夜间的睡眠比例异常高，揭示了睡眠/觉醒周期的改变。白天与夜间的睡眠比例越高，认知能力越差，这表明白天睡眠比例越高，可能预示着认知能力受损。
Sleep duration and proportion of daytime versus nighttime sleep may affect cognitive function in older patients in the transition out of the intensive care unit. To explore the relationship between the daytime-to-nighttime sleep ratio and cognitive impairment in older intensive care unit survivors. The study enrolled 30 older adults within 24 to 48 hours after intensive care unit discharge. All participants were functionally independent before admission and underwent mechanical ventilation in the intensive care unit. Actigraphy was used to estimate daytime (6 am to 9:59 pm) and nighttime (10 pm to 5:59 am) total sleep duration. Daytime-to-nighttime sleep ratios were calculated by dividing the proportion of daytime sleep by the proportion of nighttime sleep. The National Institutes of Health Toolbox Cognition Battery Dimensional Change Card Sort Test (DCCST) was used to assess cognition. Associations between sleep and cognition were explored using multivariate regression after adjusting for covariates. The mean (SD) daytime sleep duration was 7.55 (4.30) hours (range, 0.16–14.21 hours), and the mean (SD) nighttime sleep duration was 4.99 (1.95) hours (range, 0.36–7.21 hours). The mean (SD) daytime-to-nighttime sleep ratio was 0.71 (0.30) (range, 0.03–1.10). Greater daytime sleep duration (β = −0.351, P = .008) and higher daytime-to-nighttime sleep ratios (β = −0.373, P = .008) were negatively associated with DCCST scores. The daytime-to-nighttime sleep ratio was abnormally high in the study population, revealing an altered sleep/wake cycle. Higher daytime-to-nighttime sleep ratios were associated with worse cognition, suggesting that proportionally greater daytime sleep may predict cognitive impairment.
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影响因子：
1.3
作者：
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DOI：
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发表时间：
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影响因子：
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