Corrigendum to "Polymorphisms within human cytomegalovirus chemokine (UL146/UL147) and cytokine receptor genes (UL144) are not predictive of sequelae in congenitally infected children" [Virology 378 (2008) 86-96].
Corrigendum to "Polymorphisms within human cytomegalovirus chemokine (UL146/UL147) and cytokine receptor genes (UL144) are not predictive of sequelae in congenitally infected children" [Virology 378 (2008) 86-96].
复制标题
“人类巨细胞病毒趋化因子 (UL146/UL147) 和细胞因子受体基因 (UL144) 内的多态性不能预测先天性感染儿童的后遗症”的勘误表 [Virology 378 (2008) 86-96]。
DOI：
10.1016/j.virol.2008.10.007
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发表时间：
2009
期刊：
影响因子：
3.7
通讯作者：
Sparer,TimE
中科院分区：
文献类型：
--
作者：
Heo,Jinho;Petheram,Susie;Demmler,Gail;Murph,JodyR;Adler,StuartP;Bale,James;Sparer,TimE
没有信号序列和参考序列的成熟形式含有93至103个残基，显示5%的同一性（6个残基）和8%的相似性（9个残基）（图1）。所有序列被分配到11个不同的vCXCL-1进化枝（图2）。每个进化枝内的内变异小于6%。根据Dolan等人描述的14个UL 146组分配指定的基因型组编号。（2004年）。在第3、4和5组中未发现vCXCL-1序列。如果删除最远的参考组（来自第4组的NT，我们没有分配任何样本），100%共有残基的数量从6个增加到11个。这包括CXC趋化因子基序和四个半胱氨酸残基。这意味着这种分离株是其他vCXCL-1的远亲。
“The mature forms without the signal sequence and the reference sequences contain between 93 and 103 residues that show 5% identity (6 residues) and 8% similarity (9 residues)(Fig. 1). All sequences were assigned to 11 distinct vCXCL-1 clades (Fig. 2). The intravariability within each clade was less than 6%. The designated genotypic group numbers were assigned according to the 14 UL146 groups described by Dolan et al.(2004). No vCXCL-1 sequences were found in groups 3, 4, and 5.”“If the most distant reference group is removed (NT from Group 4, for which we did not assign any samples), the number of 100% consensus residues increases from 6 to 11. This includes the CXC chemokine motif and the four cysteine residues. This implies that this isolate is a very distant cousin of other vCXCL-1s.”