CYTOLOGICAL TYPING OF PRIMARY LUNG-CANCER - STUDY OF 100 CASES WITH AUTOPSY CONFIRMATION
CYTOLOGICAL TYPING OF PRIMARY LUNG-CANCER - STUDY OF 100 CASES WITH AUTOPSY CONFIRMATION
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DOI：
10.1002/dc.2840070104
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发表时间：
1991-01-01
影响因子：
1.3
通讯作者：
VIELH, P
中科院分区：
文献类型：
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作者：
DIBONITO, L;COLAUTTI, I;VIELH, P
为了评估支气管吸痰细胞学在肺癌分型中的准确性，我们将100例肺癌尸检病例的组织切片与同一患者死亡前观察到的细胞学特征进行了比较。小细胞癌的细胞学诊断准确率为100%；鳞状细胞癌90%；腺癌70%；50%为未分化大细胞癌。观察到的差异可能反映了肿瘤的内在特性，而不是支气管吸痰方法或细胞学解释引起的问题，特别是在晚期肺癌的病例中。由于检测小细胞癌的准确率最高，因此建议仅在细胞学基础上区分小细胞和非小细胞形式，并且只有在细胞形态学特征无可置疑的情况下才进行进一步的分类。
In order to assess the accuracy of bronchial aspiration cytology in typing lung cancer, tissue sections from 100 autopsy cases of lung cancer were compared with the cytology features observed in the same patients prior to death. There was 100% accuracy in the cytology of small-cell carcinoma; 90% in squamous-cell carcinoma; 70% in adenocarcinoma; and 50% in undifferentiated large-cell carcinoma. The observed discrepancies probably reflect intrinsic tumor properties rather than problems attributable to either the bronchial aspiration method or cytology interpretation, especially in cases involving advanced lung carcinoma. Because the highest accuracy rate was in detecting small-cell carcinoma, it is recommended that only the distinction between small-cell and non-small-cell forms be made on cytologic grounds and that further categorizations only be rendered in cases with unquestionable cytomorphological features.