Dietary patterns and risk of cardiovascular deaths among middle-aged Japanese: JACC Study
Dietary patterns and risk of cardiovascular deaths among middle-aged Japanese: JACC Study
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DOI：
10.1016/j.numecd.2011.10.007
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发表时间：
2013-06-01
影响因子：
3.9
通讯作者：
Tamakoshi, A.
中科院分区：
文献类型：
--
作者：
Maruyama, K.;Iso, H.;Tamakoshi, A.
背景和目的：几乎没有证据表明日本人的饮食模式与心血管疾病之间存在关联。本研究的目的是调查日本中年人的饮食模式是否与心血管疾病相关。 方法和结果：在基线（1988-1990），26,598 名男性和 37,439 名年龄在 40-79 岁的女性参加了日本协作队列 (JACC) 研究。在截至2003年的随访期间，有578名男性和499名女性死于中风，272名男性和207名女性死于冠心病。通过对男女的因素分析，我们确定了三种主要的饮食模式：“蔬菜”、“动物性食品”和“乳制品”。蔬菜模式最高与最低五分位数中总心血管疾病死亡率的多变量风险比 (HR) 和 95% 置信区间为 0.93 (0.78-1.13)，男性趋势 p = 0.73，女性为 0.82 (0.67-1.00)，趋势 p = 0.04。乳制品最高与最低五分位数中，中风死亡率的 HR 分别为 0.65 (0.49-0.86)，男性的趋势 p = 0.01，女性的 HR 为 0.70 (0.51-0.97)，趋势的 p = 0.02，总心血管疾病的 HR 分别为 0.89 (0.74-1.08)，男性和女性的趋势 p = 0.23。 0.76 (0.61-0.94)，女性趋势 p = 0.01。无论男女，动物性食物模式与中风、冠心病或总体心血管疾病死亡率均无关。结论：我们发现，“蔬菜”和“乳制品”模式与日本人心血管疾病导致的道德低下相关，而“动物性食物”模式与心血管疾病死亡率无关。 (C) 2011 Elsevier B.V. 保留所有权利。
Background and Aims: Little evidence showed the association between dietary patterns and cardiovascular disease among Japanese. The objective of this study was to examine whether dietary patterns are associated with cardiovascular disease among middle-aged Japanese.Methods and Results: At baseline (1988-1990), 26,598 men and 37,439 women aged 40-79 years enrolled in the Japan Collaborative Cohort (JACC) Study. During the follow-up through 2003, 578 men and 499 women died from stroke, and 272 men and 207 women died from coronary heart disease. We identified three major dietary patterns, 'vegetable', 'animal food' and 'dairy product', by factor analysis for both sexes. The multivariable hazard ratio (HR) and 95% confidence intervals of mortality from total cardiovascular disease in the highest versus lowest quintiles of the vegetable pattern were 0.93 (0.78-1.13), p for trend = 0.73 for men and 0.82 (0.67-1.00), p for trend = 0.04 for women. The respective HRs of mortality from stroke in the highest versus lowest quintiles of the dairy product pattern were 0.65 (0.49-0.86), p for trend = 0.01 for men and 0.70 (0.51-0.97), p for trend = 0.02 for women, and those of total cardiovascular disease were 0.89 (0.74-1.08), p for trend = 0.23 for men and 0.76 (0.61-0.94), p for trend = 0.01 for women. The animal food pattern was not associated with mortality from stroke, coronary heart disease or total cardiovascular disease for either sex.Conclusion: We found that 'vegetable' and 'dairy product' patterns were associated with lower morality from cardiovascular disease, while the 'animal food' pattern was not associated with mortality from cardiovascular disease among Japanese. (C) 2011 Elsevier B.V. All rights reserved.