Does 3-T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3T
Does 3-T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3T
复制标题
DOI：
10.1007/s00247-018-4261-2
复制
发表时间：
2019-01-01
影响因子：
2.3
通讯作者：
Victoria, Teresa
中科院分区：
文献类型：
--
作者：
Jaimes, Camilo;Delgado, Jorge;Victoria, Teresa
背景3 T的胎儿MRI与1.5T的噪声增加有关。本研究的目的是确定与1.5T的新生儿相比，产前有3 T MR的新生儿先天性听力损失的患病率是否增加。在2012年至2016年期间进行了胎儿MRI检查，并在出生后60天内进行了新生儿听力筛查。排除听力筛查不完整的胎儿、两种场强下的磁共振成像（MRI）研究或受听力损失相关疾病影响的胎儿。确定了在1.5T下扫描的随机对照组。5例受试者重复进行了相同强度的MRI（1例为3 T，4例为1.5T）。采用Fisher精确检验比较瞬态耳声发射测试和听性脑干反应测试的通过/未通过率。进行Logistic回归，以评估其他已知的危险因素对先天性hearingloss. ResultsThirty四十胎儿MRI检查进行了3 T，其中62符合纳入标准的影响。使用相同的排除标准创建了1.5-T胎儿MRI患者的对照人群，从合格人群中随机选择62例患者。瞬态耳声发射试验1.5T组和3 T组的失败率分别为9.7%和6.5%，听性脑干反应试验分别为3.2%和1.6%。两组间任一测试的失败率均无显著差异（瞬态耳声发射测试P=0.74，听性脑干反应测试P=0.8）。3-T组的中位孕龄为30周1d，显著高于对照组（P
BackgroundFetal MRI at 3T is associated with increased acoustic noise relative to 1.5T.ObjectiveThe goal of this study is to determine if there is an increased prevalence of congenital hearing loss in neonates who had a 3-T prenatal MR vs. those who had it at 1.5T.Materials and methodsWe retrospectively identified all subjects who had 3-T fetal MRI between 2012 and 2016 and also underwent universal neonatal hearing screening within 60days of birth. Fetuses with incomplete hearing screening, magnetic resonance imaging (MRI) studies at both field strengths or fetuses affected by conditions associated with hearing loss were excluded. A random group of controls scanned at 1.5T was identified. Five subjects had repeat same-strength MRIs (one at 3T and four at 1.5T). The pass/fail rate of the transient otoacoustic emissions test and auditory brainstem response test were compared using the Fisher exact test. A logistic regression was performed to assess the effects of other known risk factors for congenital hearing loss.ResultsThree hundred forty fetal MRI examinations were performed at 3T, of which 62 met inclusion criteria. A control population of 1.5-T fetal MRI patients was created using the same exclusion criteria, with 62 patients randomly selected from the eligible population. The fail rates of transient otoacoustic emissions test for the 1.5-T and 3-T groups were 9.7% and 6.5%, respectively, and for the auditory brainstem response test were 3.2% and 1.6%, respectively. There was no significant difference in the fail rate of either test between groups (P=0.74 for transient otoacoustic emissions test, and P=0.8 for auditory brainstem response test). The median gestational age of the 3-T group was 30weeks, 1day, significantly higher (P