Epistasis and hybrid sterility in Saccharomyces
Epistasis and hybrid sterility in Saccharomyces
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DOI：
10.1098/rspb.2002.1989
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发表时间：
2002-06-07
影响因子：
4.7
通讯作者：
Travisano, M
中科院分区：
文献类型：
--
作者：
Greig, D;Borts, RH;Travisano, M
杂交不育被认为是由于来自不同物种的基因之间有害的上位性相互作用造成的。在这里，我们证明了显性基因不亲和性不是酿酒酵母与五个近缘物种杂交的不育性的原因。不育的二倍体通过基因组加倍获得可育性，从而产生杂交四倍体。基于这些和以前的结果，我们得出结论，基因不亲和性和经典的染色体物种形成模型都不适用。
Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.