Site-specific recombination with the chromosomal tRNALeu gene by the large conjugative Haemophilus resistance plasmid

Site-specific recombination with the chromosomal tRNALeu gene by the large conjugative Haemophilus resistance plasmid
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DOI:
10.1128/aac.46.5.1602-1603.2002
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发表时间:
2002-05-01
影响因子:
4.9
通讯作者:
Crook, DW
Crook, DW
中科院分区:
医学2区
文献类型:
--
作者:
Dimopoulou, ID;Russell, JE;Crook, DW

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嗜血杆菌质粒p1056与流感嗜血杆菌染色体重组所涉及的序列的表征产生了表明与染色体tRNA(Leu)的位点特异性重组的证据。在6个不同来源的质粒中发现了与p1056相同的attP序列,表明嗜血杆菌质粒家族与染色体tRNA(Leu)重组。
Characterization of the sequences involved in recombination of the Haemophilus plasmid p1056 with the Haemophilus influenzae chromosome produced evidence indicating site-specific recombination with chromosomal tRNA(Leu). attP sequences identical to those of p1056 were found in six plasmids of diverse origin, suggesting that a family of Haemophilus plasmids recombines with chromosomal tRNA(Leu).