Different Clinical Characteristics between Polymicrobial and Monomicrobial Aeromonas Bacteremia -A Study of 216 Cases
Different Clinical Characteristics between Polymicrobial and Monomicrobial Aeromonas Bacteremia -A Study of 216 Cases
复制标题
DOI：
10.2169/internalmedicine.49.4117
复制
发表时间：
2010-01-01
影响因子：
1.2
通讯作者：
Tsai, Chen-Chi
中科院分区：
文献类型：
--
作者：
Lay, Chorng-Jang;Zhuang, Han-Juan;Tsai, Chen-Chi
背景部分气单胞菌菌血症是多种微生物感染。然而，单一微生物和多微生物气单胞菌菌血症的临床比较迄今为止还没有reported.Methods在台湾的三个大型转诊医院的气单胞菌菌血症患者的病历进行了回顾性分析8年期间（2001-2008年）covered.Results有154例单微生物气单胞菌菌血症和62例多微生物气单胞菌血症。在多种微生物感染中，E.大肠埃希菌是最常见的混合病原菌（42%），其次是克雷伯菌属。(24%）和肠杆菌属（Enterobacter spp.）(16%).多因素Logistic回归分析显示，实体癌是多微生物气单胞菌菌血症的危险因素，男性和肝硬化是单微生物气单胞菌菌血症的危险因素。然而，在所有类型的实体癌中，肝癌与单微生物气单胞菌菌血症相关。APACHE Ⅱ评分是两组患者最重要的预后因素。结论肝硬化患者及男性患者气单胞菌血症倾向于单菌感染。多微生物气单胞菌菌血症与实体癌有关。无论是多菌或单菌气单胞菌菌血症，预后可以预测根据疾病的严重程度，APACHE II评分。
Background Part of Aeromonas bacteremia is polymicrobial infection. However, a clinical comparison of monomicrobial and polymicrobial Aeromonas bacteremia has not hitherto been reported.Methods A retrospective analysis of medical records of patients with Aeromonas bacteremia at three large referral hospitals in Taiwan for an 8-year period (2001-2008) was conducted.Results There were 154 patients with monomicrobial Aeromonas bacteremia and 62 patients with polymicrobial Aeromonas bacteremia. In the polymicrobial infections, E. coli was the most common combined pathogen (42%), followed by Klebsiella spp. (24%) and Enterobacter spp. (16%). Multivariate logistic regression analysis revealed solid cancer as the risk factor for polymicrobial Aeromonas bacteremia, with male gender and cirrhosis as risk factors for monomicrobial Aeromonas bacteremia. However, of all types of solid cancer, hepatoma was associated with monomicrobial Aeromonas bacteremia. APACHE II score was the most important prognostic factor in both groups.Conclusion Aeromonas bacteremia in patients with cirrhosis or male gender tended to be monomicrobial. Polymicrobial Aeromonas bacteremia was associated with solid cancers. In either polymicrobial or monomicrobial Aeromonas bacteremia, prognosis could be predicted according to disease severity measured by APACHE II score.