Biologic significance of the soluble specific substances of pneumococci

Biologic significance of the soluble specific substances of pneumococci
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DOI:
10.1093/infdis/38.2.131
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发表时间:
1926-01-01
影响因子:
6.4
通讯作者:
Bailey, GH
Bailey, GH
中科院分区:
医学2区
文献类型:
--
作者:
Felton, LD;Bailey, GH

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134 LD费尔顿和GH贝利是与保留的possib是目前在这些准备以外的立场。在分析中,除了用减毒培养物注射获得略高的氮结果外,与Heidelbe描述的结果一致。因此,推测可溶性特定物质可能是由于分子的毒性基本部分,或作为Wayman和Zinsser的”残留物“的含氮部分。7但剂量为0.005 mg。大分子的水合物,其量会很小。此外,制备的批次的效价反应在血清中为000,000,在抗血清中为1:20,000,000,然而,关于该实验的准备的问题,无论结果如何,事实必须是少量的特定物质或中和或破坏各种表现。
134 LD Felton and GH Bailey is made with the reservation of the possib is present in these preparations other than stance. In the analyses of the preparatio correspond to those described by Heidelbe exception of a slightly higher nitrogen results have been obtained by the injectio with attenuated cultures in a manner sho Accordingly, the supposition might be m soluble specific substance was due to a tox essential part of the molecule, or as a con to the nitrogenous fraction of" residue an Wayman and Zinsser. 7 However, it shou dose of 0.005 mg. of the material, which is hydrate of a large molecule, the amount would be small. Furthermore, the titer reactions with the lots prepared were very 000,000 in serum and 1: 20,000,000 in anti answer, however to the question as to wha this experiment, awaits the preparation of Whatever the outcome, the fact must be bor small amount of specific substance or of neutralize or destroy the varied manifestat