Coronary disease risk assessment in men: Comparison between ASCVD Risk versus Framingham

Coronary disease risk assessment in men: Comparison between ASCVD Risk versus Framingham
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DOI:
10.1016/j.ijcard.2016.11.102
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发表时间:
2017-02-01
影响因子:
3.5
通讯作者:
Goncales Sant'Ana, Debora de Mello
Goncales Sant'Ana, Debora de Mello
中科院分区:
医学2区
文献类型:
--
作者:
Maciel Guerra-Silva, Natalia Maria;Santucci, Fernanda Sene;Goncales Sant'Ana, Debora de Mello

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简介:本研究评估了男性患冠心病的风险及其决定因素,通过两个验证的冠状动脉风险scales.Methods:一个横断面流行病学分析研究,其中数据收集自发的需求,通过半结构式问卷调查,临床检查,血液收集这些结果进行比较。采用卡方检验、Logistic回归和Kappa检验进行统计学分析。年龄是血压(BP)变化、向心性肥胖、BMI、BMI、总胆固醇、LDL和甘油三酯的决定性因素(p < 0.05)。在这组637人中,252人的血压高于推荐值。结果发现,男性总胆固醇高者占34.54%,低密度脂蛋白高者占19.94%,高密度脂蛋白低于正常值者占46.78%,甘油三酯升高者占36.42%。24.96%的男性患有代谢综合征。在Frachial量表中,637名男性接受了评估,12.56%处于中度风险,5.49%处于高风险,而在ASCVD风险量表中,553名男性接受了评估,7.05%具有中度风险,没有人具有高冠状动脉风险。在这项研究中,50.43%的男性仍然没有以前的诊断为任何疾病,增加的风险factors.Conclusions:决定性的临床变量是年龄,血压,吸烟,中心性肥胖,种族和教育。Frachial量表允许在研究中评估所有人的心脏风险,没有年龄限制或胆固醇值,因此在人群研究中,由于其包括所有个体的综合特征,它显示出优于ASCVD风险的优势。(C)2016爱思唯尔爱尔兰有限公司版权所有。
Introduction: This study evaluated the risk of men developing coronary heart disease and its determinant variables, comparing these results through two validated coronary risk scales.Methods: A cross sectional epidemiological analytical study in which data were collected by spontaneous demand, through a semi-structured questionnaire, clinical examination, and blood collection. The Chi-square test, logistic regression and Kappa for statistical analysis were performed.Results: The study included 637 men. Age was a determining factor (p < 0.05) in blood pressure (BP) changes, central obesity, BMI, glycemia, total cholesterol, LDL and triglycerides. From this group of 637, 252 presented BP above the recommended values. It was found that 34.54% of men had high total cholesterol, 19.94% had high LDL, 46.78% presentedHDL belownormal values and 36.42% had elevated triglycerides. Metabolic syndrome was found in 24.96% of the men. With the Framingham scale, 637 men were evaluated, 12.56% were at intermediate-risk and 5.49% elevated risk, while on the ASCVD Risk scale 553 men were evaluated, and 7.05% had moderate risk and none had high coronary risk. In this study, 50.43% of men still had no previous diagnosis for any disease that increases the risk factors.Conclusions: The determinant clinical variables were age, blood pressure, smoking, central obesity, race and education. The Framingham scale allowed the assessment of cardiac risk of allmen in the study, with no age restriction or cholesterol value, so in population studies it shows advantages over the ASCVD Risk due to its comprehensive feature of including all individuals. (C) 2016 Elsevier Ireland Ltd. All rights reserved.