Formulation and characterization of a novel fluoride-releasing dental composite
Formulation and characterization of a novel fluoride-releasing dental composite
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DOI：
10.1016/j.dental.2005.11.027
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发表时间：
2006-11-01
期刊：
影响因子：
5
通讯作者：
Burgess, John O.
中科院分区：
文献类型：
--
作者：
Xu, Xiaoming;Ling, Long;Burgess, John O.
目标.本研究的目的是制定一种新型的氟释放牙科复合材料，并评估其机械性能，氟释放和充电能力，吸水性和溶解性。合成了一种含三元氟化锆螯合物的二甲基丙烯酸酯单体。用不同的单体配方（wt.%）制备了三种实验性的氟化物释放复合材料。(1)对照A：40 BisGMA/40 TEDMA/20 UEDMA;（2）实验：20 F-释放单体/20 BisGMA/40 TEDMA/20 UEDMA;（3）对照B：与对照A相同的配方，不同之处在于它含有10重量% (of总单体）四丁基氟化铵（TBAF），其具有氟化物含量当量。到实验。所有三种材料具有相同的填料含量：55重量%硅烷化氟铝硅酸盐颗粒（0.8 μ m）和10重量%硅烷化热解法二氧化硅（14 nm）。所有材料均含有0.17重量%作为光引发剂的蒽醌（CQ）和0.69wt. 4-二甲基氨基苯甲酸乙酯（4 EDMAB）作为促进剂。测试了材料的氟化物释放（184天），氟化物补给，压缩和弯曲强度，吸水性和溶解度。采用方差分析、Tukey-HSD检验和Kruskal-Wallis检验进行统计学分析。实验复合材料具有比两种对照复合材料显著更高的氟化物释放和氟化物再充电能力。其物理力学性能显著优于对照B。氟化物释放二甲基丙烯酸酯单体和氟化物释放填料的组合使用可提供持续的高氟化物释放和再充电以及可接受的机械和物理性质。简单地在单体中加入有机氟盐会产生机械和物理性能较差的复合材料。(C)2005年牙科材料学院。由爱思唯尔有限公司出版。保留所有权利。
Objectives. The aims of this study were to formulate a novel fluoride-releasing dental composite and to evaluate its mechanical properties, fluoride release and recharge capabilities, water sorption and solubility.Methods. A fluoride-releasing dimethacrylate monomer containing a ternary zirconium fluoride chelate was synthesized. Three experimental fluoride-releasing composites were fabricated with different monomer formulas (wt.%)-(1) Control A: 40 BisGMA/40 TEDMA/20 UEDMA; (2) Experimental: 20 F-releasing monomer/20 BisGMA/40 TEDMA/20 UEDMA; (3) Control B: the same formula as Control A except that it contained 10wt.% (of total monomer) tetrabutylammonium fluoride (TBAF), which had a fluoride content equivalent. to Experimental. All three materials had the same filler content: 55wt.% silanized fluoroaluminosilicate particles (0.8 mu m) and 10 wt.% silanized fumed silica (14 nm). All materials contained 0.17 wt.% camphorquinone (CQ) as a photoinitiator and 0.69wt.% ethyl-4-dimethylaminobenzoate (4EDMAB) as an accelerator. The materials were tested for fluoride release (for 184 days), fluoride recharge, compressive and flexure strength, water sorption and solubility. The data were analyzed using ANOVA and Tukey-HSD tests, and Kruskal-Wallis test.Results. The experimental composite had significantly higher fluoride release and fluoride recharge capabilities than both Control composites. It had significantly better physical and mechanical properties than Control B.Significance. The combined use of the fluoride-releasing dimethacrylate monomer and fluoride-releasing filler can provide sustained high fluoride release and recharge as well as acceptable mechanical and physical properties. Simply adding organic fluoride salt in the monomer yields composites with poor mechanical and physical properties. (C) 2005 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.