WHEN IS CANCER PAIN MILD, MODERATE OR SEVERE - GRADING PAIN SEVERITY BY ITS INTERFERENCE WITH FUNCTION
WHEN IS CANCER PAIN MILD, MODERATE OR SEVERE - GRADING PAIN SEVERITY BY ITS INTERFERENCE WITH FUNCTION
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DOI：
10.1016/0304-3959(94)00178-h
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发表时间：
1995-05-01
期刊：
影响因子：
7.4
通讯作者：
CLEELAND, CS
中科院分区：
文献类型：
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作者：
SERLIN, RC;MENDOZA, TR;CLEELAND, CS
作为描述癌症疼痛严重程度的一种方法，我们探索了疼痛严重程度的数值评级与疼痛对活动、情绪和睡眠等功能的干扰评级之间的关系。干预措施被用作疼痛严重程度分级的关键变量。我们探索了将疼痛严重程度大致分为轻度、中度和重度的可能性。我们的假设是，轻度、中度和重度疼痛对癌症患者功能的损害是不同的。我们能够根据对功能的干扰来确定这些疼痛严重程度类别之间的界限。我们还研究了来自不同语言和文化群体的癌症患者在自我报告的疼痛严重程度的干扰程度上的差异。我们找到了最佳切点，形成了3个不同的疼痛严重程度，可以在0-10分的数值范围内定义。我们确定，基于对癌症患者功能的干扰程度，1-4分对应轻度疼痛，5-6分对应中度疼痛，7-10分对应重度疼痛。我们的分析表明，疼痛严重程度与干扰是非线性的关系。在我们的分析中，这些切点对于每个国家样本都是相同的，尽管在受疼痛影响的特定干扰项目上存在细微差异。这些切点可能在临床评价、流行病学和临床试验中有用。
As a way of delineating different levels of cancer pain severity, we explored the relationship between numerical ratings of pain severity and ratings of pain's interference with such functions as activity, mood, and sleep. Interference measures were used as critical variables to grade pain severity. We explored the possibility that pain severity could be classified into groupings roughly comparable to mild, moderate, and severe. Our hypothesis was that mild, moderate, and severe pain would differentially impair cancer patients' function. We were able to identify boundaries among these categories of pain severity in terms of their interference with function. We also examined the extent to which cancer patients from different language and cultural groups differ in their self-reported interference as a function of pain severity level. We found optimal cutpoints that form 3 distinct levels of pain severity that can be defined on a 0-10-point numerical scale. We determined that, based on the degree of interference with cancer patients' function, ratings of 1-4 correspond to mild pain, 5-6 to moderate pain, and 7-10 to severe pain. Our analysis illustrates that the pain severity-interference relationship is non-linear. These cutpoints were the same for each of the national samples in our analysis, although there were slight differences in the specific interference items affected by pain. These cutpoints might be useful in clinical evaluation, epidemiology, and clinical trials.