A novel stereotaxic apparatus for neuronal recordings in awake head-restrained rats.
A novel stereotaxic apparatus for neuronal recordings in awake head-restrained rats.
复制标题
一种用于清醒头部约束大鼠神经元记录的新型立体定位仪。
DOI:
10.1016/j.jneumeth.2011.02.025
复制
发表时间:
2011
影响因子:
3
通讯作者:
Shapiro,StevenM
中科院分区:
文献类型:
--
作者:
Chaniary,KunalD;Baron,MarkS;Robinson,Pete;Rice,AnnC;Wetzel,PaulA;Shapiro,StevenM
A novel technique for neuronal recordings in awake head-restrained animals is presented. Our setup allows (1) daily repeat microelectrode studies in rats without use of anesthesia, (2) excellent stabilization of head using an eight point fixation, (3) painless head-restraint of the animal, (4) accurate stereotaxic localization during multiple sessions of recording, (5) to considerably reduced surgical time, (6) quick repositioning during chronic recording sessions and (7) high quality stabilized neuronal recordings during periods of rest and active movements.