Aging: Treating the Older Patient.

Aging: Treating the Older Patient.
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DOI:
10.1016/j.bbmt.2016.11.007
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发表时间:
2017-03
期刊:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
影响因子:
--
通讯作者:
Artz A
Artz A
中科院分区:
其他
文献类型:
--
作者:
Rosko A;Artz A

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尽管自体移植在多发性骨髓瘤和同种异体移植在AML中的应用越来越多,老年评估是一种评估生理储备的多维工具,可用于评估移植的适应性。衰老生物标志物与老年指标配对可能是未来评估虚弱和衡量治疗毒性风险的新方法。造血细胞移植结果可以实现有利的老年人骨髓瘤和AML的无病生存率。
HighlightsDespite the greater use of autologous transplant for multiple myeloma and allogeneic transplant for AML, significant underuse persists.A geriatric assessment is a multidimensional tool to assess physiologic reserve and can be used to assess fitness for transplant.Aging biomarkers paired with geriatric metrics may be a novel method to assess frailty and gauge risk of treatment toxicity in the future.Hematopoietic cell transplant outcomes can achieve favorable disease-free survival rate in older adults both in myeloma and AML.
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