Symptom experience in the last year of life among individuals with cancer
Symptom experience in the last year of life among individuals with cancer
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DOI：
10.1016/j.jpainsymman.2006.05.023
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发表时间：
2006-11-01
影响因子：
4.7
通讯作者：
Verbitsky, Natalya
中科院分区：
文献类型：
--
作者：
Doorenbos, Ardith Z.;Given, Charles W.;Verbitsky, Natalya
癌症患者在生命末期往往会出现许多影响其生活质量的症状。这项研究考察了癌症患者在生命末期的症状体验，并确定症状体验是随着死亡的临近而变化，还是因抑郁症状、性别、癌症部位或年龄而不同。对来自三个前瞻性、描述性、纵向研究(n=174)的数据进行二次分析，使用三级分层线性模型。疲劳、虚弱、疼痛、呼吸急促和咳嗽是生命最后一年中最常见的五种症状。生命最后一年的症状体验与癌症部位、抑郁症状、日常生活活动的依赖性以及研究开始时的日常生活独立活动显著相关。这些发现揭示了癌症患者在生命最后一年的症状经历。随着对症状体验的更多了解，干预策略可以有针对性地实现预期的结果，即在生命结束时提高生活质量。
Individuals with cancer often experience many symptoms that impair their quality of life at the end of life. This study examines symptom experience at end of life among individuals with cancer, and determines if symptom experience changes with proximity to death, or differs by depressive symptomatology, sex, site of cancer, or age. A secondary analysis of data from three prospective, descriptive, longitudinal studies (n = 174) was performed, using a three-level hierarchical linear model. Fatigue, weakness, pain, shortness of breath, and cough were the five most prevalent symptoms in the last year of life. The symptom experience in the last year of life was significantly associated with site Of cancer, depressive symptomatology, dependencies in activities daily living, and independent activities of daily living at the start of the study. These findings shed light on the symptom experience in the last year of life for individuals with cancer. With greater understanding of the symptom experience, intervention strategies can be targeted to achieve the desired outcome of increased quality of life at the end of life.