Nuclear spin noise imaging

Nuclear spin noise imaging
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DOI:
10.1073/pnas.0601743103
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发表时间:
2006-05-02
影响因子:
11.1
通讯作者:
Jerschow, A
Jerschow, A
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Müller, N;Jerschow, A

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NMR图像从含水体模的质子自旋噪声信号中获得,该体模放置在系统变化的磁场梯度存在下的低温冷却NMR探针的高度调谐的低噪声谐振电路中。空间分辨的质子自旋密度从原始信号通过修改后的投影重建协议。虽然自旋噪声成像本质上不如传统的磁共振成像灵敏,但它提供了对不透明物体或受试者内部的完全非侵入性可视化。因此,即使由于技术或安全原因而不能应用X射线或射频辐射,断层扫描也成为可能。
NMR images were obtained from the proton spin noise signals of a water-containing phantom, which was placed in the highly tuned, low-noise resonant circuit of a cryogenically cooled NMR probe in the presence of systematically varied magnetic field gradients. The spatially resolved proton spin density was obtained from the raw signal by a modified projection-reconstruction protocol. Although spin noise imaging is inherently less sensitive than conventional magnetic resonance imaging, it affords an entirely noninvasive visualization of the interior of opaque objects or subjects. Thus, tomography becomes possible even when neither x-ray nor radio frequency radiation can be applied for technical or safety reasons.