Allelic polymorphic investigation of 21 autosomal short tandem repeat loci in a Chinese Bai ethnic group
Allelic polymorphic investigation of 21 autosomal short tandem repeat loci in a Chinese Bai ethnic group
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中国白族21个常染色体短串联重复基因座的等位基因多态性研究
DOI：
10.1016/j.legalmed.2012.08.012
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发表时间：
2013-03-01
期刊：
影响因子：
1.5
通讯作者：
Zhu, Bo-feng
中科院分区：
文献类型：
--
作者：
Shen, Chun-mei;Wang, Hong-dan;Zhu, Bo-feng
从云南大理白族自治州出生的106例无亲缘关系的白族健康人群中获得21个常染色体短串联重复序列（STRs）的群体遗传数据。共观察到138个等位基因，对应的等位频率范围为0.005 ~ 0.575。这些STR位点的基因型频率分布符合Hardy-Weinberg平衡（Hardy-Weinberg平衡检验采用Bonferroni校正）。21个STR基因座的排除概率为0.9999975729，区分力为0.999999999999999999999999872，匹配值概率为1.28 × 10（-19）。2012爱思唯尔爱尔兰有限公司版权所有。
Population genetic data of 21 autosomal short tandem repeats (STRs) were obtained in a sample of 106 unrelated healthy individuals of Bai ethnic minority born in the Dali Bai Autonomous Prefecture in Yunnan Province. We observed 138 alleles with corresponding allelic frequencies ranging from 0.005 to 0.575. The genotypic frequency distributions at those STR loci were consistent with Hardy-Weinberg equilibrium (Bonferroni's correction was used for Hardy-Weinberg equilibrium tests). The combined probability of exclusion, power of discrimination, probability of matching value for all 21 STR loci were 0.9999975729, 0.999999999999999999872 and 1.28 x 10(-19), respectively. The population data in this study showed significant differences from the previously published population data of Tibetan and Salar groups in some loci. (c) 2012 Elsevier Ireland Ltd. All rights reserved.