Reduction in consumption of sugar-sweetened beverages is associated with weight loss: the PREMIER trial
Reduction in consumption of sugar-sweetened beverages is associated with weight loss: the PREMIER trial
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DOI：
10.3945/ajcn.2008.27240
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发表时间：
2009-05-01
影响因子：
7.1
通讯作者：
Caballero, Benjamin
中科院分区：
文献类型：
--
作者：
Chen, Liwei;Appel, Lawrence J.;Caballero, Benjamin
背景：随着美国人口肥胖流行，饮料中液体热量的消耗量也随之增加，但其因果关系仍不清楚。目的：本研究的目的是探讨饮料消耗量的变化如何影响成年人的体重变化。设计：这是一项前瞻性研究，参加了 PREMIER 试验，这是一项为期 18 个月的随机、对照、行为干预试验。在基线、6 个月和 18 个月进行测量（体重、身高和 24 小时饮食回忆）。结果：液体卡路里的基线平均摄入量为 356 kcal/d（占总能量摄入的 19%）。在控制了潜在的混杂因素和干预分配后，每天减少 100 kcal 的液体热量与 6 个月时体重减轻 0.25 kg（95% CI：0.11，0.39；P < 0.001）和 18 个月时体重减轻 0.24 kg（95% CI：0.06，0.41；P = 0.008）相关。减少液体热量摄入比减少固体热量摄入对减肥的效果更强。在各种饮料中，只有含糖饮料（SSB）的摄入量与体重变化显着相关。每天减少 1 份 SSB 摄入量与第 6 个月时体重减轻 0.49 公斤（95% CI：0.11, 0.82；P = 0.006）和 18 个月时体重减轻 0.65 公斤（95% CI：0.22, 1.09；P = 0.003）有关。 结论：这些数据支持限制成人液体热量摄入并减少摄入量的建议。 SSB 消耗作为实现重量的手段 减轻或避免体重过度增加。该试验在 ClinicalTrials.gov 上注册为 NCT00000616。美国临床营养杂志 2009；89：1299-306。
Background: Consumption of liquid calories from beverages has increased in parallel with the obesity epidemic in the US population, but their causal relation remains unclear.Objective: The objective of this study was to examine how changes in beverage consumption affect weight change among adults.Design: This was a prospective study of 810 adults participating in the PREMIER trial, an 18-mo randomized, controlled, behavioral intervention trial. Measurements (weight, height, and 24-h dietary recall) were made at baseline, 6 mo, and 18 mo.Results: Baseline mean intake of liquid calories was 356 kcal/d (19% of total energy intake). After potential confounders and intervention assignment were controlled for, a reduction in liquid calorie intake of 100 kcal/d was associated with a weight loss of 0.25 kg (95% CI: 0.11, 0.39; P < 0.001) at 6 mo and of 0.24 kg (95% CI: 0.06, 0.41; P = 0.008) at 18 mo. A reduction in liquid calorie intake had a stronger effect than did a reduction in solid calorie intake on weight loss. Of the individual beverages, only intake of sugar-sweetened beverages (SSBs) was significantly associated with weight change. A reduction in SSB intake of 1 serving/d was associated with a weight loss of 0.49 kg (95% CI: 0.11, 0.82; P = 0.006) at 6 mo and of 0.65 kg (95% CI: 0.22, 1.09; P = 0.003) at 18 mo.Conclusions: These data support recommendations to limit liquid calorie intake among adults and to reduce SSB consumption as a means to accomplish weight loss or avoid excess weight gain. This trial was registered at clinicaltrials.gov as NCT00000616. Am J Clin Nutr 2009;89:1299-306.