Digital Microfluidics
Digital Microfluidics
复制标题
DOI：
10.1146/annurev-anchem-062011-143028
复制
发表时间：
2012-01-01
期刊：
影响因子：
--
通讯作者：
Wheeler, Aaron R.
中科院分区：
文献类型：
--
作者：
Choi, Kihwan;Ng, Alphonsus H. C.;Wheeler, Aaron R.
数字微流体（DMF）是一种新兴的液体处理技术，它可以单独控制开放电极阵列上的液滴。这些皮升到微升大小的液滴，每一个都充当化学过程的隔离容器，可以移动、合并、分裂和从容器中分配。由于其独特的优势，包括简单的仪器，灵活的器件几何形状，以及易于与其他技术耦合，DMF被应用于广泛的领域。在这篇综述中，我们从分析化学的角度总结了DMF技术的最新进展，包括液滴驱动理论、器件制造和集成以及应用。
Digital microfluidics (DMF) is an emerging liquid-handling technology that enables individual control over droplets on an open array of electrodes. These picoliter- to microliter-sized droplets, each serving as an isolated vessel for chemical processes, can be made to move, merge, split, and dispense from reservoirs. Because of its unique advantages, including simple instrumentation, flexible device geometry, and easy coupling with other technologies, DMF is being applied to a wide range of fields. In this review, we summarize the state of the art of DMF technology from the perspective of analytical chemistry in sections describing the theory of droplet actuation, device fabrication and integration, and applications.