Synthesis and antioxidant activity of hydroxycinnamic acid xylan esters.
Synthesis and antioxidant activity of hydroxycinnamic acid xylan esters.
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DOI：
10.1021/jf9043953
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发表时间：
2010-05
影响因子：
6.1
通讯作者：
Pauli Wrigstedt;Petri Kylli;L. Pitkänen;P. Nousiainen;M. Tenkanen;J. Sipilä
中科院分区：
文献类型：
--
作者：
Pauli Wrigstedt;Petri Kylli;L. Pitkänen;P. Nousiainen;M. Tenkanen;J. Sipilä
已知天然存在的羟基肉桂酸，如阿魏酸和芥子酸具有抗氧化活性。在这项研究中，阿魏酸和芥子酸共价连接到燕麦斯佩耳特阿拉伯木聚糖和桦木木葡糖醛酸木聚糖的酯化反应，在一个两步可行的合成，以产生不同程度的取代改性木聚糖。通过FT-IR、NMR和HPSEC实验对所得衍生物进行了全面分析，以确认木聚糖的酯化反应和取代度。使用乳剂脂质氧化试验评价缀合物的抗氧化潜力。结果表明，衍生的木聚糖抑制脂质氧化显着优于天然燕麦斯佩耳特和桦木木聚糖。结果发现，葡糖醛酸木聚糖的阿魏酸酯比阿拉伯木聚糖的那些更有效的抗氧化剂，芥子酸木聚糖酯比它们的阿魏酸对应物更有效。
Naturally occurring hydroxycinnamic acids, such as ferulic and sinapic acids, are known to possess antioxidant activity. In this study, ferulic acid and sinapic acid were covalently attached to oat spelt arabinoxylan and birch wood glucuronoxylan by esterification in a two-step feasible synthesis to generate modified xylans with various degrees of substitution. The obtained derivatives were fully analyzed by FT-IR, NMR, and HPSEC experiments to confirm the esterification of xylans and the degree of substitution. The antioxidative potential of the conjugates was evaluated using the emulsion lipid oxidation test. The results demonstrate that the derivatized xylans inhibited lipid oxidation notably better than the native oat spelt and birch wood xylans. It was found that ferulic acid esters of glucuronoxylan were more efficient antioxidants than those of arabinoxylan and that sinapic acid xylan esters were more efficient than their ferulic acid counterparts.