Cross-coupling/annulations of quinazolones with alkynes for access to fused polycyclic heteroarenes under mild conditions.
Cross-coupling/annulations of quinazolones with alkynes for access to fused polycyclic heteroarenes under mild conditions.
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DOI：
10.1039/c3ob41955j
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发表时间：
2014-01
影响因子：
3.2
通讯作者：
Hui Lu;Qin Yang;Yirong Zhou;Yanqin Guo;Z. Deng;Q. Ding;Yiyuan Peng
中科院分区：
文献类型：
--
作者：
Hui Lu;Qin Yang;Yirong Zhou;Yanqin Guo;Z. Deng;Q. Ding;Yiyuan Peng
研究了钌催化喹唑酮类化合物与炔烃的区域选择性氧化交偶联/环反应，从而直接得到多环杂环芳烃。在温和的条件下，广泛的衬底范围进行了良好的转化，实现了中高产量。
Ruthenium-catalyzed regioselective oxidative cross-coupling/annulations of quinazolones with alkynes were successfully developed for direct access to fused polycyclic heteroarenes. The transformation proceeded well with a broad substrate scope under mild conditions to achieve moderate to high yields.