Porcine cortical bone ablation by ultrashort pulsed laser irradiation
Porcine cortical bone ablation by ultrashort pulsed laser irradiation
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DOI：
10.1117/1.jbo.17.2.028001
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发表时间：
2012-02-01
影响因子：
3.5
通讯作者：
Fang, Qiyin
中科院分区：
文献类型：
--
作者：
Emigh, Brent;An, Ran;Fang, Qiyin
超短脉冲激光在骨消融术中显示出在许多骨科应用的前景。为了最大限度地减少侧支组织损伤和控制消融过程，消融阈值流量必须得到很好的表征。利用放大的飞秒激光(170fs，800 nm，1 kHz)，用D-2方法测量了不变猪皮质骨的消融阈值，多个入射脉冲数为25~1000个/光斑。脉冲数越大，阈值越低，说明存在潜伏期效应。用幂函数模型计算出未改变的猪皮质骨的孵化系数为0.89+/-0.03。通过外推，单脉冲消融阈值为3.29+/-0.14J/cm(2)。(C)2012年，光学仪器工程师学会。[DOI：10.1117/1.JBO.17.2.028001]
Ultrashort pulsed lasers in bone ablation show promise for many orthopedic applications. To minimize collateral tissue damage and control the ablation process, the ablation threshold fluence must be well characterized. Using an amplified femtoseconcl laser (170 fs, 800 nm, 1 kHz), the ablation threshold on unaltered porcine cortical bone was measured using the D-2 method at multiple incident pulse numbers ranging from 25 to 1000 pulses per spot. The lowered threshold at greater pulse numbers indicated an incubation effect. Using a power law model, the incubation coefficient of unaltered porcine cortical bone was found to be 0.89 +/- 0.03. Through extrapolation, the single-pulse ablation threshold was found to be 3.29 +/- 0.14 J/cm(2). (c) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.2.028001]