High Intensity Interval- vs Moderate Intensity- Training for Improving Cardiometabolic Health in Overweight or Obese Males: A Randomized Controlled Trial.
High Intensity Interval- vs Moderate Intensity- Training for Improving Cardiometabolic Health in Overweight or Obese Males: A Randomized Controlled Trial.
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DOI：
10.1371/journal.pone.0138853
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Allison DB
中科院分区：
文献类型：
--
作者：
Fisher G;Brown AW;Bohan Brown MM;Alcorn A;Noles C;Winwood L;Resuehr H;George B;Jeansonne MM;Allison DB
比较6周高强度间歇训练（HIIT）与持续中等强度训练（MIT）对改善久坐超重或肥胖年轻男性队列的身体成分、胰岛素敏感性（SI）、血压、血脂和心血管健康的影响。我们假设HIIT与MIT组相比，在身体成分、心血管健康、血脂和SI方面会产生类似的改善，尽管与MIT组每周5小时的活动相比，HIIT每周只需要1小时的活动。28名久坐超重或肥胖男性（年龄，20 ± 1.5岁，体重指数29.5 ± 3.3 kg/m2）参加了为期6周的运动治疗。参与者被随机分配到HIIT或MIT，并在基线和培训后进行评估。DXA用于评估身体成分，分级平板运动试验用于测量心血管健康，口服葡萄糖耐量用于测量SI，核磁共振波谱法用于评估脂蛋白颗粒，自动听诊用于测量血压。在完整病例分析中，与HIIT相比，MIT观察到VO 2峰值的改善更大（11.1% vs 2.83%，P = 0.0185）。在意向治疗分析中未观察到差异，也未观察到其他组间差异。两种运动条件均与体脂百分比、总胆固醇、中等VLDL、中等HDL、甘油三酯、SI和VO 2峰值的时间改善相关（P < 0.05）。参与HIIT或MIT运动训练显示：1）改善SI，2）降低血脂，3）降低体脂百分比，4）改善心血管健康。虽然两个运动组在评估的大多数心脏代谢风险因素方面都有类似的改善，但MIT在整体心血管健康方面有更大的改善。总体而言，这些观察结果表明，相对较短的HIIT或MIT训练时间可能会改善先前久坐的超重或肥胖年轻男性的心脏代谢风险因素，这两种特定方案之间没有明显的优势（临床试验注册号NCT 01935323）。ClinicalTrials.gov NCT01935323
To compare the effects of six weeks of high intensity interval training (HIIT) vs continuous moderate intensity training (MIT) for improving body composition, insulin sensitivity (SI), blood pressure, blood lipids, and cardiovascular fitness in a cohort of sedentary overweight or obese young men. We hypothesized that HIIT would result in similar improvements in body composition, cardiovascular fitness, blood lipids, and SI as compared to the MIT group, despite requiring only one hour of activity per week compared to five hours per week for the MIT group. 28 sedentary overweight or obese men (age, 20 ± 1.5 years, body mass index 29.5 ± 3.3 kg/m2) participated in a six week exercise treatment. Participants were randomly assigned to HIIT or MIT and evaluated at baseline and post-training. DXA was used to assess body composition, graded treadmill exercise test to measure cardiovascular fitness, oral glucose tolerance to measure SI, nuclear magnetic resonance spectroscopy to assess lipoprotein particles, and automatic auscultation to measure blood pressure. A greater improvement in VO2peak was observed in MIT compared to HIIT (11.1% vs 2.83%, P = 0.0185) in the complete-case analysis. No differences were seen in the intention to treat analysis, and no other group differences were observed. Both exercise conditions were associated with temporal improvements in % body fat, total cholesterol, medium VLDL, medium HDL, triglycerides, SI, and VO2peak (P < 0.05). Participation in HIIT or MIT exercise training displayed: 1) improved SI, 2) reduced blood lipids, 3) decreased % body fat, and 4) improved cardiovascular fitness. While both exercise groups led to similar improvements for most cardiometabolic risk factors assessed, MIT led to a greater improvement in overall cardiovascular fitness. Overall, these observations suggest that a relatively short duration of either HIIT or MIT training may improve cardiometabolic risk factors in previously sedentary overweight or obese young men, with no clear advantage between these two specific regimes (Clinical Trial Registry number NCT01935323). ClinicalTrials.gov NCT01935323