Stability of gel wax based optical scattering phantoms.

Stability of gel wax based optical scattering phantoms.
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DOI:
10.1364/boe.9.003495
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发表时间:
2018-08-01
影响因子:
3.4
通讯作者:
Munro PRT
Munro PRT
中科院分区:
医学2区
文献类型:
--
作者:
Jones CJM;Munro PRT

文献摘要

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具有可调谐光学散射特性的幻影在光学成像技术的发展和改进中是必不可少的。基于矿物油的“凝胶蜡”幽灵由于其易于制造和制造速度,无毒性质,能够铸造成解剖学上真实的形状,以及其生产成本效益的性质而越来越受到关注。在凝胶蜡中加入诸如二氧化钛粉和单分散二氧化硅微球之类的散射体,可以产生具有可控光学散射系数的幻影。为了能够重复使用这种幽灵,必须确定散射特性的稳定性——这一特性还有待研究。我们提出了这种幻影的降低散射系数()随时间的稳定性分析。我们得出结论,由于可测量的散射系数随时间的降低,嵌入二氧化硅球的凝胶蜡幻影可能不适合随着时间的推移重复使用,但是凝胶蜡- tio2幻影在时间上更稳定。
Phantoms with tuneable optical scattering properties are essential in the development and refinement of optical based imaging techniques. Mineral oil based ‘gel wax’ phantoms are the subject of increasing interest due to their ease and speed of manufacture, non-toxic nature, ability to cast into anatomically realistic shapes, as well as their cost-effective nature of production. The addition of scatterers such as titanium dioxide powder and monodisperse silica microspheres to the gel wax allows for the creation of phantoms with a controllable optical scattering coefficient. To enable repeated use of such phantoms, the stability of the scattering properties must be determined–a property which has yet to be investigated. We present an analysis of the stability of the reduced scattering coefficient () of such phantoms over time. We conclude that due to the measurable reduction in scattering coefficient over time, gel wax phantoms embedded with silica spheres may not be suitable for repeated use over time, however gel wax-TiO2 phantoms are much more temporally stable.