Antioxidant vitamin levels in term and preterm infants and their relation to maternal vitamin status
Antioxidant vitamin levels in term and preterm infants and their relation to maternal vitamin status
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DOI：
10.1016/s0188-4409(02)00356-9
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发表时间：
2002-05-01
影响因子：
7.7
通讯作者：
Canatan, H
中科院分区：
文献类型：
--
作者：
Baydas, G;Karatas, F;Canatan, H
背景脂质过氧化在许多新生儿并发症的发病机制中起着至关重要的作用。早产儿特别容易患肺病和视网膜病，可能是由于他们的抗氧化系统缺乏。维生素E、维生素A和维生素C是天然抗氧化防御系统的一部分。我们的目的是确定足月儿和早产儿的母亲和脐带血血浆中维生素E、A和C的水平，并研究这些水平之间的关系。在本研究中，我们测定了维生素E，A和C水平的脐带血足月（n = 30）和早产儿（n = 22）和他们的母亲的HPLC。在分娩过程中采集血样。脐血中脂溶性抗氧化剂维生素E和维生素A的水平低于母体值（p
Background. Lipid peroxidation plays a vital role in the pathogenesis of many neonatal complications. Preterm babies are especially predisposed to lung diseases and retinopathy, probably due to a deficiency in their antioxidant systems. Vitamins E, A, and C are part of the natural antioxidant defense systems. We aimed to determine the levels of vitamins E, A, and C in maternal and cord blood plasma of term and preterm infants and to investigate the relationships between these levels.Methods. In the present study we determined vitamin E, A, and C levels in the Umbilical cord blood of term (n = 30) and preterm (n = 22) infants and their mothers by HPLC. Blood samples were taken during delivery.Results. Levels of lipid soluble antioxidant vitamin E and A in cord blood were lower than maternal values (p