HEAD AND NECK CANCERS - RESULTS OF THERMORADIOTHERAPY VERSUS RADIOTHERAPY

HEAD AND NECK CANCERS - RESULTS OF THERMORADIOTHERAPY VERSUS RADIOTHERAPY
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DOI:
10.3109/02656739009140944
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发表时间:
1990-05-01
影响因子:
3.1
通讯作者:
GUPTA, S
GUPTA, S
中科院分区:
医学2区
文献类型:
--
作者:
DATTA, NR;BOSE, AK;GUPTA, S

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一项随机临床研究纳入了 65 名患者,以评估局部热疗联合放疗治疗头颈部癌症的疗效。局部热疗42-43℃。 C 由 27 .cntdot 生成。 12 MHz 射频透热治疗仪,在 33 名患者放疗前使用;其余32名患者仅接受放射治疗。两组早期病变(I 期和 II 期)患者的反应相似,而晚期疾病(III 期和 IV 期)患者通过联合治疗获得了明显更好的肿瘤控制。
Sixty-five patients were included in a randomized clinical study to evaluate the efficacy of local hyperthermia as a concomitant agent to radiotherapy in the treatment of carcinoma of the head and neck region. Local hyperthermia at 42-43.degree. C was generated by a 27 .cntdot. 12 MHz radiofrequency diathermy unit and was used before radiotherapy in 33 patients; the remaining 32 patients were subjected to radiotherapy alone. The response in patients with early lesions (Stage I and II) was similar for both the groups, while in patients with advanced diseases (Stage III and IV) a significantly better tumour control was obtained by the use of the combined treatment.