The weakest link: Haploid honey bees are more susceptible to neonicotinoid insecticides
The weakest link: Haploid honey bees are more susceptible to neonicotinoid insecticides
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DOI：
10.1016/j.chemosphere.2019.125145
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发表时间：
2020-03-01
期刊：
影响因子：
8.8
通讯作者：
Straub, Lars
中科院分区：
文献类型：
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作者：
Friedli, Andrea;Williams, Geoffrey R.;Straub, Lars
新烟碱类杀虫剂目前是野生和管理昆虫健康的主要关注点，这些昆虫提供关键的生态系统服务，如授粉。尽管类烟碱的亚致死作用是众所周知的，但关于它们如何影响发育稳定性以及遗传学在多大程度上参与的信息却令人惊讶地少之又少。这对于单倍体个体尤其如此，因为它们在解毒位点是半合子的，可能更易感。在这里，我们利用西方蜜蜂的单倍性，意大利蜜蜂，首次表明，类烟碱影响二倍体女性（工人）的发育稳定性，而单倍体男性（雄蜂）更容易受到影响。表型前翅脉序异常和波动的翅膀不对称，作为措施的发展不稳定性，显着增加下现场现实的类烟碱暴露的殖民地。单倍体雄蜂的较高易感性表明杂合性在缓冲类烟碱亚致死效应的能力中发挥关键作用。为了改善保护工作，我们的研究结果强调迫切需要更好地了解遗传学在使非目标生物能够科普杀虫剂暴露方面所起的作用。(C)2019年，任作家。爱思唯尔有限公司出版
Neonicotinoid insecticides are currently of major concern for the health of wild and managed insects that provide key ecosystem services like pollination. Even though sublethal effects of neonicotinoids are well known, there is surprisingly little information on how they possibly impact developmental stability, and to what extent genetics are involved. This holds especially true for haploid individuals because they are hemizygous at detoxification loci and may be more susceptible. Here we take advantage of haplodiploidy in Western honey bees, Apis mellifera, to show for the first time that neonicotinoids affect developmental stability in diploid females (workers), and that haploid males (drones) are even more susceptible. Phenotypic fore wing venation abnormalities and fluctuating wing asymmetry, as measures of developmental instability, were significantly increased under field-realistic neonicotinoid-exposure of colonies. The higher susceptibility of haploid drones suggests that heterozygosity can play a key role in the ability to buffer the sublethal effects of neonicotinoids. Aiming to improve conservation efforts, our findings highlight the urgent need to better understand the role that genetics plays at enabling nontarget organisms to cope with insecticide exposure. (C) 2019 The Authors. Published by Elsevier Ltd.