Global climate and infectious disease: The cholera paradigm
Global climate and infectious disease: The cholera paradigm
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DOI：
10.1126/science.274.5295.2025
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发表时间：
1996-12-20
期刊：
影响因子：
56.9
通讯作者：
Colwell, RR
中科院分区：
文献类型：
--
作者：
Colwell, RR
霍乱的起源一直难以捉摸，尽管科学证据清楚地表明它是一种水传播疾病。然而，在两次流行病之间，从包括水在内的环境样本中分离霍乱弧菌的标准细菌学程序通常是不成功的。霍乱弧菌是一种需要盐才能生长的海洋弧菌，当条件不利于生长和繁殖时，它会进入休眠、有活力但不可培养的阶段。霍乱弧菌与浮游生物，特别是桡足类动物的联系，为霍乱的环境起源提供了进一步的证据，也解释了霍乱流行的零星和不稳定发生。在全球范围内，霍乱流行现在可以与气候和气候事件（如El Niño）以及浮游生物宿主的全球分布有关。利用卫星图像的遥感有可能预测有利于霍乱爆发或流行的条件。
The origin of cholera has been elusive, even though scientific evidence clearly shows it is a waterborne disease. However, standard bacteriological procedures for isolation of the cholera vibrio from environmental samples, including water, between epidemics generally were unsuccessful.Vibrio cholerae, a marine vibrio, requiring salt for growth, enters into a dormant, viable but nonculturable stage when conditions are unfavorable for growth and reproduction. The association ofVibrio choleraewith plankton, notably copepods, provides further evidence for the environmental origin of cholera, as well as an explanation for the sporadic and erratic occurrence of cholera epidemics. On a global scale, cholera epidemics can now be related to climate and climatic events, such as El Niño, as well as the global distribution of the plankton host. Remote sensing, with the use of satellite imagery, offers the potential for predicting conditions conducive to cholera outbreaks or epidemics.