Prevalence and potential determinants of subthreshold and major depression in the general population of Qatar
Prevalence and potential determinants of subthreshold and major depression in the general population of Qatar
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DOI：
10.1016/j.jad.2019.04.056
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发表时间：
2019-06-01
影响因子：
6.6
通讯作者：
Khaled, Salma M.
中科院分区：
文献类型：
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作者：
Khaled, Salma M.
背景：在没有战争的阿拉伯国家，抑郁症的流行病学研究很少。这项研究估计了在卡塔尔和邻近海湾国家典型的移民和非移民中亚阈值（SUBDE）和重度抑郁发作（MDE）的患病率和潜在决定因素。方法：2017年2月对2，424名参与者进行了基于概率的电话调查。样本根据国籍和收入分为：低收入移民（LIM），高收入移民（希姆斯）和非移民或卡塔尔国民（QN）。参与者完成了9项医生健康问卷（PHQ-9）。收集种族、社会人口统计学、健康和工作相关信息。结果：任何抑郁症的总体患病率范围为4.2%（95%CI：3.3-5.3）和6.6%（95%CI：5.4-7.9）的截止值为12和10，分别。SUBDE和MDE的诊断算法得出的估计值分别为5.5%（95% CI：4.4-6.8）和3.6%（95% CI：2.8-4.5）。与非迁移者相比，LIMs（OR =2.96，p = 0.004）和希姆斯（OR = 2.00，p = 0.014）的SUBDE（而非MDE）率显著增加。相对于南亚人（OR = 3.77，p < 0.001）和其他种族（OR = 3.61，p = 0.029），阿拉伯种族与SUBDE显著相关。阿拉伯种族与MDE显著相关：相对于南亚人（OR = 10.42，p < 0.001）和东南亚人（OR = 3.54，p = 0.007）。局限性：抑郁症的临床诊断访谈不包括在内。结论：使用PHQ-9，在卡塔尔的抑郁症患病率与西方国家的一般人群估计值相当。移民身份和种族与SUBDE和MDE相关，并对早期筛查和社区干预产生影响。
Background: There is a paucity of epidemiological studies of depression in war-free Arab countries. This study estimated the prevalence and potential determinants of Subthreshold (SUBDE) and Major Depressive Episode (MDE) in migrants and non-migrants typical of Qatar and neighboring Gulf countries.Methods: A telephone survey of a probability-based sample of 2,424 participants was conducted in February 2017. The sample was divided based on nationality and income: Low-Income Migrants (LIMs), High Income Migrants (HIMs), and non-migrants or Qatari Nationals (QNs). Participants completed the nine-item Physician Health Questionnaire (PHQ-9). Ethnicity, sociodemographics, health- and work-related information was collected. Bivariate and multinomial logistic regression analyses were used.Results: Overall prevalence of any depression ranged between 4.2% (95% CI: 3.3-5.3) and 6.6% (95% CI: 5.4-7.9) for a cut-off of 12 and 10, respectively. The diagnostic algorithm for SUBDE and MDE resulted in estimates of 5.5% (95% CI: 4.4-6.8) and 3.6% (95% CI: 2.8-4.5), respectively. SUBDE, but not MDE rates, were significantly increased in LIMs (OR =2.96, p = 0.004) and HIMs (OR = 2.00, p = 0.014) compared with non-migrants. Arab ethnicity was significantly associated with SUBDE: relative to South Asians (OR = 3.77, p < 0.001) and other ethnicities (OR = 3.61, p = 0.029). Arab ethnicity was significantly associated with MDE: relative to South Asians (OR = 10.42, p < 0.001) and South East Asians (OR = 3.54, p = 0.007).Limitations: Clinical diagnostic interviews for depression were not included.Conclusion: Using the PHQ-9, depression prevalence in Qatar was comparable to general population estimates from Western countries. Migrant status and ethnicity were associated with SUBDE and MDE with implications for early screening and community intervention.