Temperature regulation in the mouse,Peromyscus leucopus: Effects of various photoperiods, pinealectomy and melatonin administration

Temperature regulation in the mouse,Peromyscus leucopus: Effects of various photoperiods, pinealectomy and melatonin administration
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小鼠白鼠的温度调节:不同光周期、松果体切除术和褪黑激素给药的影响

DOI:
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发表时间:
1980
影响因子:
3.2
通讯作者:
S. Gendler
S. Gendler
中科院分区:
地球科学3区
文献类型:
--
作者:
G. Lynch;J. K. Sullivan;S. Gendler

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白足鼠(Peromyscus leucopus)对一系列递减的光周期表现出两种反应。在LD 13:11 - LD 12:12和LD 10:14 - 9:15 LD的光周期之间,小鼠的日困倦和无脂棕色脂肪重量逐渐增加。维持在LD 9:15光周期下的松果体切除小鼠未表现出假手术动物的特征性每日麻木程度和筑巢增加。长期植入含有3毫克褪黑激素的蜂蜡丸替代疗法可逆转松果体切除术的影响。
The white-footed mouse,Peromyscus leucopus, exhibits two responses to a decreasing series of photoperiods. The “winter” molt and reproductive regression occur in mice maintained on a photoperiods of 12 hours of light per day or less. Daily torpor and weight of lipid-free brown fat increase gradually between photoperiods of LD 13:11 — LD 12:12 and LD 10:14 — 9:15 LD. Pinealectomized mice maintained on a LD 9:15 photoperiod fail to exhibit the extent of daily torpor and increased nesting which are characteristic of sham-operated animals. Replacement therapy with chronically implanted beeswax pellets containing 3 mg of melatonin reverses the effects of pinealectomy.