Interarticulator co-ordination in deaf signers with Parkinson's disease.
Interarticulator co-ordination in deaf signers with Parkinson's disease.
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患有帕金森病的聋哑手语者的发音器间协调。
DOI：
10.1016/s0028-3932(99)00022-6
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发表时间：
1999
期刊：
影响因子：
2.6
通讯作者：
Poizner,H
中科院分区：
文献类型：
--
作者：
Tyrone,ME;Kegl,J;Poizner,H
运动控制缺陷与帕金森氏病（PD）的签署者进行了检查，通过分析他们的生产美国手语（ASL）的手指拼写，这是顺序和快速的运动行为，其基础结构的理论模型。分析了两名聋人签名者与两名聋人对照签名者的自由对话。此外，一个控制签名者的脚本生产也进行了分析，并直接比较相同的生产与PD签名者。ASL指法拼写的特征分析和多个咬合架运动的逐帧分析被用来检查指法拼写产品。在特征分析的基础上，PD的签名者表现出各种错误模式，所有这些都反映了试图减少运动的要求，从而促进清晰度。患有PD的手势者要么长时间保持手指拼写序列中的各个片段（分割），将相邻片段混合成单个片段（顺序混合），要么将手形顺序分解成其组成特征（特征解开）。特征分析和逐帧分析的结果都表明，PD签名者在协调复杂序列中独立发音器官的运动时存在困难。例如，手指拼写的独立发音器官（拇指，手指和手腕）的运动在时间上明显更远，并且PD签名者的变化更大。此外，PD签名者在手指拼写时使用较少的手腕运动。这种缺陷与PD患者使用持续感觉运动信息来编程多咬合架运动的能力受损的说法一致。
Motor control deficits in signers with Parkinson’s disease (PD) were examined through analysis of their production of American Sign Language (ASL) fingerspelling, which is sequential and rapid motor behavior that has theoretical models of its underlying structure. Free conversation of two Deaf signers with PD and two Deaf control signers was analysed. In addition, scripted productions of one control signer were also analysed and directly compared to the same productions by the signers with PD. A featural analysis of ASL fingerspelling and a frame-by-frame analysis of multiple articulator movements were used to examine the fingerspelled productions. On the basis of the featural analysis, the signers with PD showed a variety of error patterns, all of which reflected attempts to reduce the motoric demands of coarticulation and thereby facilitate ease of articulation. Signers with PD either held individual segments in a fingerspelling sequence for a long time (segmentation), blended adjacent segments into a single segment (sequential blending), or broke handshapes down sequentially into their component features (featural unraveling). The results of both the featural analysis and the frame-by-frame analysis show that the PD signers have difficulty co-ordinating the movements of independent articulators in complex sequences. For example, the movements of independent articulators for fingerspelling (the thumb, fingers, and wrist) were markedly farther apart in time and more variable for the signers with PD. In addition, the signers with PD used fewer wrist movements while fingerspelling. Such deficits are consistent with claims that patients with PD are impaired in their ability to use ongoing sensorimotor information to program multi-articulator movements.