Deprived of a good stroke outcome.

Deprived of a good stroke outcome.
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剥夺了良好的中风结果。

DOI:
10.1161/strokeaha.114.008312
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发表时间:
2015
期刊:
影响因子:
8.3
通讯作者:
Morgenstern,LewisB
Morgenstern,LewisB
中科院分区:
医学1区
文献类型:
--
作者:
Skolarus,LesliE;Morgenstern,LewisB

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尽管中风后死亡率的下降值得庆祝,1但我们必须时刻牢记,对许多人来说,严重的中风后残疾被认为是比死亡更糟糕的结果。 2 因此,需要更加关注中风幸存者,特别是他们的认知和身体功能。中风幸存者面临着许多与癌症幸存者相同的挑战,也许中风幸存者可以模仿我们的肿瘤学同事正在进行的广泛的幸存者护理和研究。 3在本期《中风》中,Chen 等人 4 使用南伦敦中风登记处 16 年的数据来探讨社会经济地位 (SES) 和中风后残疾的作用。在这篇出色的文章中,作者发现 SES 与通过 Barthel 指数衡量的 90 天和 3 年功能障碍相关。与最贫困的中风幸存者组相比,最贫困的中风幸存者组功能结果不佳的几率增加了 75% 以上。在考虑了中风后残疾的重要预测因素(包括年龄、中风严重程度和病前功能障碍)后,这种关联仍然存在。在分层分析中,SES 与女性、年龄≥ 65 岁患者、无合并症患者和缺血性中风患者的功能障碍相关,但与其他群体无关。格拉斯哥昏迷评分和言语缺陷用于调整中风严重程度,而不是使用美国国立卫生研究院中风量表评分等更全面的严重程度衡量标准,这可能解释了他们的部分重要发现。
Although the decline in poststroke mortality is a cause for celebration, 1 we must remain mindful that substantial poststroke disability is considered a worse outcome than death for many people. 2 Thus, an increased focus on stroke survivors, in particular, their cognitive and physical function, is needed. Stroke survivors face many of the same challenges as cancer survivors, and perhaps stroke survivorship could be modeled after the ongoing extensive survivorship care and research done by our oncology colleagues. 3In this issue of Stroke, Chen et al 4 used 16 years of data from the South London Stroke registry to explore the role of socioeconomic status (SES) and poststroke disability. In this well-done article, the authors found that SES was associated with 90-day and 3-year functional impairment as measured by the Barthel Index. When compared with the least deprived group of stroke survivors, the most deprived group of stroke survivors had over a 75% increase in the odds of poor functional outcome. This association remained after accounting for prominent predictors of poststroke disability, including age, stroke severity, and premorbid functional impairment. In stratified analysis, SES was associated with functional impairment in women, patients aged≥ 65 years, patients without comorbidities, and patients with an ischemic stroke but not other groups. Glasgow Coma Score and speech deficit were used to adjust for stroke severity rather than a more comprehensive severity measure like the National Institutes of Health Stroke Scale score, and this may explain a part of their significant findings.
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