MICROPUNCTURE STUDY OF INULIN ABSORPTION IN RAT KIDNEY

MICROPUNCTURE STUDY OF INULIN ABSORPTION IN RAT KIDNEY
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DOI:
10.1126/science.147.3659.753
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发表时间:
1965-01-01
期刊:
影响因子:
56.9
通讯作者:
LASSITER, WE
LASSITER, WE
中科院分区:
综合性期刊1区
文献类型:
--
作者:
GUTMAN, Y;GOTTSCHALK, CW;LASSITER, WE

文献摘要

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通过显微注射技术,菊糖-羧基-Cl_4或菊糖-甲氧基-H_3以不同的尿流量注入大鼠单个近曲小管。从两个肾脏分别采集的尿液显示非注射侧的菊粉活性可忽略不计,因此直接证明在这些条件下肾小管上皮细胞对菊粉没有显著的重吸收。
By means of a microinjection technique, inulin-carboxyl-Cl4 or inulin-methoxy-H3 was injected into single proximal tubules of the rat at various urine flow rates. Urine collected separately from the 2 kidneys showed negligible amounts of inulin activity on the noninjected side, thus demonstrating directly that there is no significant reabsorption of inulin by the renal tubular epithelium under these conditions.