MUCOEPIDERMOID CARCINOMA OF SALIVARY GLAND ORIGIN - CLASSIFICATION, CLINICAL-PATHOLOGIC CORRELATION, AND RESULTS OF TREATMENT
MUCOEPIDERMOID CARCINOMA OF SALIVARY GLAND ORIGIN - CLASSIFICATION, CLINICAL-PATHOLOGIC CORRELATION, AND RESULTS OF TREATMENT
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DOI：
10.1002/1097-0142(197008)26:2
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发表时间：
1970-01-01
期刊：
影响因子：
6.2
通讯作者：
SMITH, L
中科院分区：
文献类型：
--
作者：
HEALEY, WV;PERZIN, KH;SMITH, L
本文报告60例涎腺粘液表皮样癌。将病理结果与临床病程分开检查，然后将其关联起来。肿瘤被分类为分化良好、中度或分化不良。用于分类病变的标准进行了讨论，并说明了病理特征。影响预后的主要因素有：1.组织学分化程度; 2.手术切除线上有无肿瘤。复发与组织分化程度有关。31例患者中只有1例（3%）在仔细检查手术标本时未能在切除线上显示肿瘤时复发。相反，28例手术切缘肿瘤患者中有19例（68%）复发。其他9例患者均未复发，立即接受后续治疗。治疗建议是基于肿瘤的组织学分级和手术切除线的检查。
Sixty patients with mucoepidermoid carcinoma of salivary gland origin were studied. The pathologic findings and the clinical course were examined separately and then correlated. The tumors are classified as either well, moderately, or poorly differentiated. The criteria used to classify the lesions are discussed, and pathologic features are illustrated. The most important factors in the prognosis are: 1. degree of histologic differentiation, and 2. presence or absence of tumor on the lines of surgical excision. Recurrences correlated with the degree of histologic differentiation. Only one of 31 patients (3%) had a recurrence when careful examination of the surgical specimen failed to demonstrate tumor on the lines of resection. In contrast, 19 of 28 patients (68%) with tumor on the surgical margin had a recurrence. The other 9 patients had no recurrence, having been given immediate subsequent treatment. Recommendations made for therapy are based on the histologic grade of the tumor and on examination of surgical lines of resection.