Investigations of interference between electromagnetic transponders and wireless MOSFET dosimeters: a phantom study.
Investigations of interference between electromagnetic transponders and wireless MOSFET dosimeters: a phantom study.
复制标题
电磁应答器和无线 MOSFET 剂量计之间的干扰研究：一项模型研究。
DOI：
10.1118/1.3578602
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发表时间：
2011
期刊：
影响因子：
3.8
通讯作者：
Anscher,Mitchell
中科院分区：
文献类型：
--
作者：
Su,Zhong;Zhang,Lisha;Ramakrishnan,V;Hagan,Michael;Anscher,Mitchell
目的为了评价Calypso系统（Calypso Medical Technologies，Inc.，西雅图，华盛顿州）在存在剂量验证系统（DVS，Sicel Technologies，Inc.，莫里斯维尔，北卡罗来纳州）和剂量计的阅读的准确性，在无线电磁应答器内的phantoms.MethodsA定制，固体水体模制造与空间的应答器和剂量计。两个插入件被加工成具有精确匹配应答器和剂量计的尺寸的定位凹槽，并且分别以正交和平行方向布置。为了测试有/没有剂量计的应答器定位准确度（假设1），在每个预设距离对有和没有剂量计的应答器导出的定位数据进行多变量分析，以检测对照组和测试组之间的统计学显著定位差异。为了测试存在/不存在应答器的剂量计剂量阅读准确度（假设2），实施了在7次相同剂量（100 cGy）输送和测量中交替存在应答器的方法。进行双因素方差分析，以检查两组和不同部分之间的统计学显著性剂量阅读差异。一个相对剂量分析方法也被用来评估应答器对剂量阅读准确性的影响后，剂量衰减效应被删除的二阶多项式fitt.ResultsMultivariate分析表明，假设1是假的，有一个统计学显着差异的控制和测试集的本地化数据。然而，对照组和测试组之间局部位置差异的95%置信区间的上限和下限均小于0.1 mm，显著小于0.5 mm的最小临床定位分辨率。对于假设2，方差分析表明，在有和没有应答器的情况下，剂量计读数之间没有统计学显著差异。正交和平行配置的多项式拟合剂量与测量剂量值的差异在1.75%以内。结论体模研究表明，由于DVS无线MOSFET剂量计的存在，Calypso系统的定位精度在临床上不受影响，剂量计测量剂量不受应答器存在的影响。因此，相同的患者可以植入应答器和剂量计，以受益于联合使用两个系统所提供的放射治疗的准确性提高。
PurposeTo evaluate both the Calypso Systems' (Calypso Medical Technologies, Inc., Seattle, WA) localization accuracy in the presence of wireless metal–oxide–semiconductor field‐effect transistor (MOSFET) dosimeters of dose verification system (DVS, Sicel Technologies, Inc., Morrisville, NC) and the dosimeters' reading accuracy in the presence of wireless electromagnetic transponders inside a phantom.MethodsA custom‐made, solid‐water phantom was fabricated with space for transponders and dosimeters. Two inserts were machined with positioning grooves precisely matching the dimensions of the transponders and dosimeters and were arranged in orthogonal and parallel orientations, respectively. To test the transponder localization accuracy with/without presence of dosimeters (hypothesis 1), multivariate analyses were performed on transponder‐derived localization data with and without dosimeters at each preset distance to detect statistically significant localization differences between the control and test sets. To test dosimeter dose‐reading accuracy with/without presence of transponders (hypothesis 2), an approach of alternating the transponder presence in seven identical fraction dose (100 cGy) deliveries and measurements was implemented. Two‐way analysis of variance was performed to examine statistically significant dose‐reading differences between the two groups and the different fractions. A relative‐dose analysis method was also used to evaluate transponder impact on dose‐reading accuracy after dose‐fading effect was removed by a second‐order polynomial fit.ResultsMultivariate analysis indicated that hypothesis 1 was false; there was a statistically significant difference between the localization data from the control and test sets. However, the upper and lower bounds of the 95% confidence intervals of the localized positional differences between the control and test sets were less than 0.1 mm, which was significantly smaller than the minimum clinical localization resolution of 0.5 mm. For hypothesis 2, analysis of variance indicated that there was no statistically significant difference between the dosimeter readings with and without the presence of transponders. Both orthogonal and parallel configurations had difference of polynomial‐fit dose to measured dose values within 1.75%.ConclusionsThe phantom study indicated that the Calypso System's localization accuracy was not affected clinically due to the presence of DVS wireless MOSFET dosimeters and the dosimeter‐measured doses were not affected by the presence of transponders. Thus, the same patients could be implanted with both transponders and dosimeters to benefit from improved accuracy of radiotherapy treatments offered by conjunctional use of the two systems.