Preponderance of acute proximal left anterior descending coronary arterial lesions in fatal myocardial infarction: a clinicopathologic study.
Preponderance of acute proximal left anterior descending coronary arterial lesions in fatal myocardial infarction: a clinicopathologic study.
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致命性心肌梗死中急性左前降支冠状动脉近端病变的优势：一项临床病理学研究。
DOI：
10.1016/0002-9149(81)90246-0
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Bulkley,BH
中科院分区：
文献类型：
--
作者：
Schuster,EH;Griffith,LS;Bulkley,BH
为确定冠状动脉树某一特定段的急性病变是否比其他阻塞更容易引起致命性心肌梗塞，对77例急性心肌梗塞死亡的尸检病人进行了研究。92%的患者存在多处冠状动脉狭窄，第一个间隔穿支之前的冠状动脉左前降支近端仅占临界狭窄（大于管腔直径的70%）的23%。相反，与致死性心肌梗死相关的急性血栓性冠状动脉事件最常发生在近端左前降支，占急性病变的61%;与此相比，8%的急性病变发生在左前降支中段或远端，18%发生在右前降支，6%的人在左回旋支和7%的人在左冠状动脉主干。在尸检的患者中，32例（40%）有77次非致命性心肌梗死，其中只有17例（22%）是与冠状动脉左前降支近端闭塞相关的前间隔梗死。急性冠状动脉左前降支近端病变的心肌梗死面积较其他急性冠状动脉病变的心肌梗死面积大，但与其他急性冠状动脉病变的心肌梗死面积无显著差异。在这些患者中，近端左前降支冠状动脉疾病占严重心肌梗死的17%，仅占非致命性梗死的22%。这些结果表明，急性冠状动脉左前降支近端病变比冠状动脉树其他部位的严重阻塞更可能导致致命性心肌梗死。由于梗死的数量似乎不足以解释这些差异，因此建议在前间隔心肌中存在质的差异。
To determine whether an acute lesion in a specific segment of the cororiary tree is more likely than other obstructions to cause fatal myocardial infarction, 77 autopsy patients Who died of acute myocardial infarction were studied. Multiple coronary stenoses were present in 92 percent of these patients, arid the proximal left anterior descending coronary artery before the first septal perforator accounted for only 23 percent of the critical narrowings (greater than 70 percent of luminal diameter). In contrast, acute thrombotic coronary events associated with fatal myocardial infarction occurred most often in the proximal left anterior descending artery, accounting for 61 percent of acute lesions; this rate compared with 8 percent of acute lesions occurring in the mid or distal left anterior descending artery, 18 percent of those in the right, 6 percent of those in the left circumflex and 7 percent of those in the left main coronary artery. Of the autopsy patients, 32 (40 percent) had 77 prior nonfatal myocardial infarcts of which only 17 (22 percent) were anteroseptal infarcts related to occlusion of the proximal left anterior descending coronary artery. The amount of infarcted myocardium in the hearts with acute proximal left anterior descending coronary arterial lesions was somewhat more extensive but not significantly different from that of hearts with other acute coronary lesions.Fifty survivors of myocardial infarction who underwent cardiac catheterization were studied for comparison. In those patients, proximal left anterior descending coronary disease accounted for 17 percent of critical narrowings and only 22 percent of nonfatal infarcts. These findings suggest that an acute proximal left anterior descending coronary arterial lesion is more likely to result in fatal myocardial infarction than are critical obstructions elsewhere in the coronary arterial tree. Because the quantity of the infarct does not appear to be sufficient to explain these differences, qualitative differences in anteroseptal myocardium are suggested.
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590 例连续非手术冠心病病例随访 5-9 年的进展研究：心室造影和其他相关性
影响因子：
37.8
作者：
A. V. Bruschke;W. Proudfit;F.;Mason SON'ES
通讯作者：
Mason SON'ES
心肌病变与冠状动脉疾病的关系II．
影响因子：
--
作者：
J. Mitchell;C. Schwartz;L.A.D Lad;ML PMMM.L.;M. L. P. M. L. L. Marg;R. PM.LRM.LRCT;Circ;L. P. M. P. M. R. fI;R. Marg;PD R M.L R M.L
通讯作者：
PD R M.L R M.L
冠状动脉疾病的手术治疗：纯移植手术，对 741 名患者进行了 3--7 年随访的研究。
影响因子：
9.1
作者：
William C. Sheldon;Gustavo Rincon;A. Pichard;Mehdi Razavi;Chalit Cheanvechai;Floyd D. Loop
通讯作者：
Floyd D. Loop
影响因子：
39.2
作者：
Bean, WB
通讯作者：
Bean, WB
致命性急性心肌梗死中冠状动脉血栓的频率和意义以及其他观察结果：对 107 名尸检患者的研究。
DOI：
10.1016/0002-9343(72)90033-2
发表时间：
1972
期刊：
The American journal of medicine
影响因子：
--
作者：
W. Roberts;L. Buja
通讯作者：
L. Buja