Virus-induced secondary bacterial infection: a concise review.
Virus-induced secondary bacterial infection: a concise review.
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DOI：
10.2147/tcrm.s87789
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发表时间：
2015
影响因子：
2.8
通讯作者：
Alhammadi AH
中科院分区：
文献类型：
--
作者：
Hendaus MA;Jomha FA;Alhammadi AH
呼吸道疾病是儿童发病和死亡的一个非常常见的原因。当遇到发热的婴儿或呼吸道感染的儿童时，卫生保健提供者经常面临两难境地。许多临床医生表示的原因是确认发烧是由病毒还是细菌引起的麻烦。本文综述的目的是更新目前的证据，病毒引起的细菌感染。我们提出了几个临床以及体外研究，支持病毒和继发性细菌感染之间的相关性。此外，我们还讨论了病毒-细菌共存的病理生理和预防模式。对PubMed和MEDLINE数据库进行了检索，以查找涵盖与呼吸道病毒相关的细菌感染的已发表文章。这项综述应使临床医生全面了解可能出现病毒性呼吸道疾病的细菌和病毒合并感染或继发感染的范围。
Respiratory diseases are a very common source of morbidity and mortality among children. Health care providers often face a dilemma when encountering a febrile infant or child with respiratory tract infection. The reason expressed by many clinicians is the trouble to confirm whether the fever is caused by a virus or a bacterium. The aim of this review is to update the current evidence on the virus-induced bacterial infection. We present several clinical as well in vitro studies that support the correlation between virus and secondary bacterial infections. In addition, we discuss the pathophysiology and prevention modes of the virus–bacterium coexistence. A search of the PubMed and MEDLINE databases was carried out for published articles covering bacterial infections associated with respiratory viruses. This review should provide clinicians with a comprehensive idea of the range of bacterial and viral coinfections or secondary infections that could present with viral respiratory illness.