[Benign granular cell anal tumor].
[Benign granular cell anal tumor].
复制标题
DOI：
--
复制
发表时间：
2003-02
期刊：
影响因子：
2.7
通讯作者：
A. Al bouzidi;K. Choho;N. Cherradi;M. Rimani;A. Harket;A. Amarti Riffi;A. Labraimi;A. Achour;A. Saidi;S. Ben Omar
中科院分区：
文献类型：
--
作者：
A. Al bouzidi;K. Choho;N. Cherradi;M. Rimani;A. Harket;A. Amarti Riffi;A. Labraimi;A. Achour;A. Saidi;S. Ben Omar
引言颗粒细胞瘤（GCT）很少位于肛周区域。1例56岁男性患者，在过去3年中，肛门右缘出现一个丘疹，大小逐渐增大（1.5cm）。细胞增殖定位于真皮层，S100蛋白强表达。它被上覆表皮的假上皮瘤样增生所覆盖。局部手术切除后40个月，没有复发的迹象。评论颗粒细胞瘤是罕见的，通常是良性的。当发生在皮肤或粘膜时，浅表样本上覆盖上皮的假上皮瘤样增生可能被误诊为鳞状细胞癌。恶性骨巨细胞瘤在组织学上可能与良性骨巨细胞瘤相同，只有出现转移（通常在局部复发后）才允许随后诊断为恶性。
INTRODUCTION Granular cell tumors (GCT) are rarely located in the perianal area. OBSERVATION Over the past 3 years, a 56 year-old man presented a papule of the right margin of the anus that had progressively increased in size (1.5 cm). Cell proliferation was located in the dermis and strongly expressed the S100 protein. It was covered by a pseudo-epitheliomatous hyperplasia of the overlying epidermis. Forty months after local surgical excision, there was no sign of recurrence. COMMENTS Granular cell tumors are rare and usually benign. When cutaneous or mucosal, the pseudo-epitheliomatous hyperplasia of the overlying epithelium may, on superficial samples, be mistakenly diagnosed as squamous cell carcinomas. Malignant GCT may, histologically, appear identical to a benign GCT and only the appearance of metastases (generally after local recurrence) permits the subsequent diagnosis of malignancy.