Effect of sleeve gastrectomy on type 2 diabetes as an alternative treatment modality to Roux-en-Y gastric bypass: systemic review and meta-analysis
Effect of sleeve gastrectomy on type 2 diabetes as an alternative treatment modality to Roux-en-Y gastric bypass: systemic review and meta-analysis
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DOI：
10.1016/j.soard.2015.03.001
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发表时间：
2015-11-01
影响因子：
3.1
通讯作者：
Rosenthal, Raul J.
中科院分区：
文献类型：
--
作者：
Cho, Jun-Min;Kim, Hyun Jung;Rosenthal, Raul J.
背景：直到最近，Roux-en-Y胃旁路术（RYGB）是减肥手术中最常用的手术。在过去的十年里，袖式胃切除术（SG）已经成为一种更流行、更简单、更少病态的减肥手术。目的：比较SG和RYGB治疗2型糖尿病（T2D）的疗效。研究背景：系统评价和荟萃分析。方法：检索截至2013年12月的MEDLINE、EMBASE和Cochrane Library。搜索词包括“袖式胃切除术”、“胃旁路”和“2型糖尿病”。选择的文章描述了“袖式胃切除术”和“胃旁路”，并包括超过1年的随访数据。使用Review Manager 5.2和SPSS version 20进行数据分析。结果：数据集包括3项回顾性临床研究、6项前瞻性临床研究和2项随机对照试验（rct），其中SG组429例，RYGB组428例。在非随机临床研究中，与标准RYGB相比，SG在缓解T2D方面显示出相似的疗效。在随机对照试验中，SG的作用低于RYGB。两种手术的T2D缓解与体重减轻的百分比无关。结论：根据目前的证据，SG对T2D缓解的作用与RYGB相似。(C) 2015年美国代谢与减肥外科学会。版权所有。
Background: Until recently, Roux-en-Y gastric bypass (RYGB) was the most frequently performed procedure in bariatric surgery. In the last decade, sleeve gastrectomy (SG) has emerged as a more popular, simpler, and less morbid form of bariatric surgery.Objectives: This study compares the efficacy of SG and RYGB for the treatment of type 2 diabetes mellitus (T2D).Setting: Systemic review and meta-analysis.Methods: MEDLINE, EMBASE, and the Cochrane Library were searched for entries up to December 2013. Search terms included "Sleeve gastrectomy," "Gastric bypass," and "Type 2 diabetes mellitus." The chosen articles described both "Sleeve gastrectomy" and "Gastric bypass" and included over 1 year of follow-up data. Data analysis was performed with Review Manager 5.2 and SPSS version 20.Results: The data set is comprised of 3 retrospective clinical studies, 6 prospective clinical studies, and 2 randomized controlled trials (RCTs), which involved 429 patients in the SG group and 428 patients in the RYGB group. In nonrandomized clinical studies, SG displayed similar efficacy in remission of T2D compared with the standard RYGB. In the RCTs, SG had a lower effect than that of RYGB. T2D remission was not correlated with the percent of excess weight loss for either procedure.Conclusions: Based on the current evidence, SG has a similar effect on T2D remission as RYGB. (C) 2015 American Society for Metabolic and Bariatric Surgery. All rights reserved.