Towards a consensus structure of hypericin in solution:: direct evidence for a single tautomer and different ionization states in protic and nonprotic solvents by the use of variable temperature gradient 1H NMR
Towards a consensus structure of hypericin in solution:: direct evidence for a single tautomer and different ionization states in protic and nonprotic solvents by the use of variable temperature gradient 1H NMR
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DOI：
10.1016/s0040-4020(02)00419-2
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发表时间：
2002-06-10
期刊：
影响因子：
2.1
通讯作者：
Troganis, A
中科院分区：
文献类型：
--
作者：
Skalkos, D;Tatsis, E;Troganis, A
金丝桃素是一种萘二蒽酮衍生物，在有机溶剂中具有两种电子光谱，这是由于存在两种互变异构体结构。可变温度梯度的H-1 NMR研究表明，只有一个7，14-二氧代互变异构体的形式的发生，在质子和非质子溶剂中的金丝桃素的分子，不同的只是在海湾地区的4-羟基的电离度。(C)2002爱思唯尔科技有限公司。保留所有权利。
Hypericin, a meso-naphthodianthrone derivative, displays two types of electronic spectra in organic solvents, attributed to the existence of two tautomeric structures. Variable temperature gradient H-1 NMR studies demonstrate the occurrence of only one 7,14-dioxo tautomeric form, for the molecule of hypericin in protic and in nonprotic solvents, differing only in the degree of ionization of the 4-hydroxyl group in the bay region. (C) 2002 Elsevier Science Ltd. All rights reserved.