Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz
Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz
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DOI：
10.1016/s0009-2614(00)00227-x
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发表时间：
2000-03-31
影响因子：
2.8
通讯作者：
Heilweil, EJ
中科院分区：
文献类型：
--
作者：
Markelz, AG;Roitberg, A;Heilweil, EJ
我们报告的第一次使用脉冲太赫兹光谱检查低频集体振动模式的生物分子。在0.06-2.00 THz（2-67 cm（-1））频率范围内，小牛胸腺DNA、牛血清白蛋白和胶原蛋白冻干粉样品的宽带吸收随频率增加而增加，表明这些系统的大量低频集体模是红外活性的。在室温下的透射率测量表明随着水合和变性，FIR吸收增加。(C)2000年由Elsevier Science B. V.出版，版权所有。
We report the first use of pulsed terahertz spectroscopy to examine low-frequency collective vibrational modes of biomolecules. Broadband absorption increasing with frequency was observed for lyophilized powder samples of calf thymus DNA, bovine serum albumin and collagen in the 0.06-2.00 THz (2-67 cm(-1)) frequency range, suggesting that a large number of the low-frequency collective modes for these systems are IR active. Transmission measurements at room temperature showed increasing FIR absorption with hydration and denaturing. (C) 2000 published by Elsevier Science B.V. All rights reserved.