Non-viral COVID-19 vaccine delivery systems.
Non-viral COVID-19 vaccine delivery systems.
复制标题
非病毒性COVID-19疫苗递送系统。
DOI:
10.1016/j.addr.2020.12.008
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发表时间:
2021-03
影响因子:
16.1
通讯作者:
Moon JJ
中科院分区:
文献类型:
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作者:
Park KS;Sun X;Aikins ME;Moon JJ
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of cases and more than one million deaths in less than a year of its report in December 2019. Since then, companies and research institutions have raced to develop SARS-CoV-2 vaccines, ranging from conventional viral and protein-based vaccines to those that are more cutting edge, including DNA- and mRNA-based vaccines. Each vaccine exhibits a different potency and duration of efficacy, as determined by the antigen design, adjuvant molecules, vaccine delivery platforms, and immunization method. In this review, we will introduce a few of the leading non-viral vaccines that are under clinical stage development and discuss delivery strategies to improve vaccine efficacy, duration of protection, safety, and mass vaccination.
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影响因子:
5.5
作者:
Carstens, Myrra G.;Camps, Marcel G. M.;Jiskoot, Wim
通讯作者:
Jiskoot, Wim
DOI:
10.1016/s0923-2516(97)89892-5
发表时间:
1997-03-01
期刊:
RESEARCH IN VIROLOGY
影响因子:
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作者:
Fazio, VM
通讯作者:
Fazio, VM
影响因子:
3.6
作者:
Garg, Rajni;Kaur, Manpreet;Bhatnagar, Rakesh
通讯作者:
Bhatnagar, Rakesh
影响因子:
10.8
作者:
Dong Y;Dorkin JR;Wang W;Chang PH;Webber MJ;Tang BC;Yang J;Abutbul-Ionita I;Danino D;DeRosa F;Heartlein M;Langer R;Anderson DG
通讯作者:
Anderson DG
DOI:
10.1038/nrmicro2090
发表时间:
2009-03
期刊:
Nature reviews. Microbiology
影响因子:
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作者:
通讯作者:
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