The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality
The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality
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DOI：
10.1007/s40520-020-01570-8
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发表时间：
2020-05-06
影响因子：
4
通讯作者：
Smith, Lee
中科院分区：
文献类型：
--
作者：
Ilie, Petre Cristian;Stefanescu, Simina;Smith, Lee
世卫组织宣布SARS-CoV-2为全球大流行。目前的目的是提出一个假设，即各国维生素D的平均水平与COVID-19引起的病例和死亡率之间存在潜在关联。获得了20个欧洲国家的维生素D平均水平以及COVID-19导致的发病率和死亡率。观察到每个国家维生素D平均水平（平均56 mmol/L，STDEV 10.61）与COVID-19病例数/1 M（平均295.95，STDEV 298.7）和死亡率/1 M（平均5.96，STDEV 15.13）呈负相关。老年人的维生素D水平非常低，特别是在西班牙、意大利和瑞士。这也是与COVID-19相关的人口中最脆弱的群体。建议对不同疾病严重程度的COVID-19患者的维生素D水平进行专门研究。
WHO declared SARS-CoV-2 a global pandemic. The present aim was to propose an hypothesis that there is a potential association between mean levels of vitamin D in various countries with cases and mortality caused by COVID-19. The mean levels of vitamin D for 20 European countries and morbidity and mortality caused by COVID-19 were acquired. Negative correlations between mean levels of vitamin D (average 56 mmol/L, STDEV 10.61) in each country and the number of COVID-19 cases/1 M (mean 295.95, STDEV 298.7, and mortality/1 M (mean 5.96, STDEV 15.13) were observed. Vitamin D levels are severely low in the aging population especially in Spain, Italy and Switzerland. This is also the most vulnerable group of the population in relation to COVID-19. It should be advisable to perform dedicated studies about vitamin D levels in COVID-19 patients with different degrees of disease severity.